关键词: 生长迟缓, 儿童, Meta分析

Abstract: Objective To understand the prevalence of growth retardation among children and adolescents in China through Meta analysis, in order to provide scientific basis for early prevention and treatment of growth retardation in children. Methods Literatures about the prevalence of growth retardation among children in China were retrieved from CNKI, Wanfang data, CBM, VIP and PubMed databases up to March 30th, 2020.Literature quality was evaluated according to the cross-sectional study evaluation criteria in STROBE statement.The prevalence rate was combined with Stata 12.0 software.Subgroup analysis was carried out on factors such as gender, age, regional distribution, year of investigation and residence.Egger test and funnel plot were used to evaluate the publication bias of each literature.The sensitivity analysis was completed by eliminating any one of low-quality articles. Results A total of 23 articles were included, with a total sample size of 699 974, ranging from 6 082 to 99 542(M=17 329).The overall prevalence of growth retardation in Chinese children was 6.0% (95%CI:5.0%-7.0%).Subgroup analysis showed that the prevalence rates of growth retardation in children aged 0-7 years and 7-18 years were 8.1%(95%CI:6.0%-10.2%) and 3.3%(95%CI:2.7%-3.9%), and the difference was significant(t＝4.12,P<0.05).The prevalence rate of growth retardation was 9.9%(95%CI:7.5%-12.2%) in 2005—2010, and 3.0%(95%CI:2.2%-3.7%) in 2011-2019, the difference was significant (t＝6.49,P<0.05).The prevalence rate of growth retardation was 4.5% (95%CI:3.4%-5.7%) in rural area and 2.5%(95%CI:1.9%-3.1%) in urban area,the defference was significant(t＝2.94,P<0.05).But the difference was not significant between different genders and regional distribution. Conclusion The prevalence rate of children's growth retardation is decreasing in China, and there are differences among different age groups and residence.

Key words: stunting, children, Meta-analysis