早产儿营养与智能发育

中国儿童保健杂志 ›› 2012, Vol. 20 ›› Issue (3): 199-201.

早产儿营养与智能发育

童笑梅

北京大学第三医院儿科,北京 100191

收稿日期:2012-01-09 发布日期:2012-03-06 出版日期:2012-03-06
作者简介:童笑梅(1964-),女,山东人,儿科主任,主任医师,硕士生导师,主要研究方向为新生儿疾病、新生儿营养策略、早产儿系统管理与早期干预

Received:2012-01-09 Online:2012-03-06 Published:2012-03-06

摘要/Abstract

摘要： 营养管理是提高早产儿存活率和改善其预后的关键环节之一,尤其与良好的智能发育密切相关。以往调查显示几乎所有早产儿在生后早期的生长发育均落后于宫内胎儿的生长曲线,说明早产儿营养支持措施仍有改进余地;本文讨论了与早产儿神经发育相关的各种营养素,氧、葡萄糖、脂肪和氨基酸及各种矿物质等,阐明早产儿强化营养支持已成为共识,众多国际卫生组织机构均倡导在NICU进行母乳喂养,强化母乳喂养能优化蛋白质摄入,促进体格尤其是头围增长和骨骼矿化,促进早产儿的神经运动发育和减少成年后代谢综合征的发病风险。推进住院早产儿母乳喂养势在必行。

关键词: 早产儿, 低出生体重儿, 小于胎龄儿, 智能发育

中图分类号:

R179

童笑梅. 早产儿营养与智能发育[J]. 中国儿童保健杂志, 2012, 20(3): 199-201.

参考文献

[1] Geary CA,Fonseca RA,Caskey MA,et al.Improved growth and decreased morbidities in <1 000 g neonates after early management changes[J].J Perinatology,2008,28(3):347-353.
[2] Agostoni C,Buonocore G,Carnielli VP,et al.Enteral nutrient supply for preterm infants:commentary from the european society for paediatric gastroenterology,hepatology,and nutrition.committee on nutrition[J].JPGN,2010,50(1):85-91.
[3] William W.Hay JR.Strategies for feeding the preterm infant[J].Neonatology,2008,94:245-254.
[4] 中华儿科杂志编辑委员会,中华医学会儿科学分会新生儿学组,中华医学会儿科学分会儿童保健学组.早产/低出生体重儿喂养建议[J].中华儿科杂志,2009,49(7):508-510.
[5] Lucas A.Programming by early nutrition:An experimental approach[J].J Nutrit,1998,128(2):401-406.
[6] Patel MS,Srinivasan M,Laychock SG,et al.Metabolic programming:Role of nutrition in the immediate postnatal life[J].Inherit Metab Dis,2009,32:218-228.
[7] Isaacs EB,Gadian DG,Sabatini S,et al.The effect of early human diet on caudate volumes and IQ[J].Pediatr Res,2008,63:229-231.
[8] Deshpande G,Simmer K.Lipids for parenteral nutrition in neonates[J].Current Opinion in Clinical Nutrition and Metabolic Care,2011,4:145-150.
[9] Vlaardingerbroek H,van Goudoever JB,vanden Akker CH.Initial nutritional management of the preterm infant[J].Early Hum Dev,2009,85(11):691-695.
[10] Boudry G,David ES,Douard V,et al.Role of intestinal transporters in neonatal nutrition:carbohydrates,proteins,lipids,minerals,and vitamins[J].JPGN,2010,51(4):380-401.
[11] Parish A,Bhatia J.Early aggressive nutrition for the premature infant[J].Neonatology,2008,94:211-214.
[12] Cooke RJ.Catch-up growth:implications for the preterm and term infant[J].Eur J Clin Nutr,2010,64(S):8-10.
[13] Arslanoglu S,Moro GE,Ziegler EE.Adjustable fortification of human milk fed to preterm infants:does it make a difference?[J].J Perinatology,2006,26:614-621.
[14] Meier PP,Engstrom JL,Patel AL,et al.Improving the use of human milk during and after the NICU stay[J].Clin Perinatol,2010,37:217-245.
[15] Davanzoa R,Ronfanib L,Brovedania P,et al.Breast feeding very-low-birthweight infants at discharge:a multicentre study using WHO definitions[J].Paediatric and Perinatal Epidemiology,2009,23:591-596.
[16] Imdada A,Sadiqb K,Bhutta ZA,et al.Evidence-based prevention of childhood malnutrition[J].Current Opinion in Clinical Nutrition and Metabolic Care,2011,14:276-285