关键词: 孤独症, 筛查, CAST, 儿童

Abstract: Objective To investigate the reliability and validity of Childhood Autism Spectrum Test(CAST)as a screening tool in China. Methods CAST Chinese version was developed by translating,back translating,and comparing repeatedly.A sample of 38 autistic children were recruited as patient group,twelve mental retarded children and fifty-nine typical developing children were recruited as control group in Hangzhou.Their parents completed CAST Chinese version. Results Internal consistency reliability and criterion-related validity of CAST Chinese version were good.Twenty-five of thirty-one scoring items had good discrimination index.At a designated cut-point of 16,the sensitivity of CAST Chinese version was 0.974,the specificity was 0.983 and positive predictive value (PPV) was 0.974.There was no significant difference between children younger and older than 4 years old. Conclusions Chinese version of Childhood Autism Spectrum Test(CAST)has good reliability and validity.It can be used to screen autistic children older than 2.5 years old.However,several items need to be improved in further study.

Key words: autism, screen, Childhood Autism Spectrum Test, children