关键词: 维生素D, 超重, 肥胖, 儿童

Abstract: Objective To explore the association of the status of vitamin D with overweight and obese children in Guangzhou,and to provide measures for the prevention of vitamin D deficiency. Methods A cross sectional study was used to investigate physical examination and laboratory test among the children in Guangzhou.Chemiluminescence was used to detect the level of serum 25-hydroxy vitamin D [25-(OH)D]. Results The average level of serum 25-(OH)D was (98.57±39.96) nmol/L with (98.58±39.64)nmol/L in boys and (98.56±40.58)nmol/L in girls and there was no statistical difference between different genders(P>0.05).The prevalence rates of vitamin D deficiency and insufficiency were 8.68% and 21.14% respectively,and there was no statistical difference between different genders (P>0.05).With the increasing of age,the level of serum 25-(OH)D decreased (P<0.05),and the prevalence rates of vitamin D deficiency and insufficiency increased (P<0.05).The level of serum 25-(OH)D was lower in overweight and obese children than those in normal children (P<0.05).The prevalence rates of vitamin D deficiency and insufficiency in overweight and obese children were higher than those in normal children (P<0.05).There was negative correlation between 25-(OH)D and BMI (P<0.001). Conclusions The status of vitamin D is poor in school children as well as overweight and obese children in Guangzhou.Comprehensive measures should be taken to improve the status in vitamin D of children especially of school children,overweight and obese children in Guangzhou.

Key words: vitamin D, overweight, obesity, children