Chinese Journal of Child Health Care ›› 2022, Vol. 30 ›› Issue (10): 1049-1052.DOI: 10.11852/zgetbjzz2022-1127

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Association of perinatal ureaplasma urealyticum infection with adverse pregnancy outcomes and neonatal related disorders

LI Qiu-ping   

  1. Faculty of Pediatrics, Chinese PLA General Hospital; Department of Pediatrics, 7th Medical Center of Chinese PLA General Hospital; National Engineering Laboratory for Birth Defects Prevention and Control of Key Technology; Beijing Key Laboratory of Pediatric Organ Failure, Beijing 100700, China
  • Received:2022-09-12 Revised:2022-09-14 Online:2022-10-10 Published:2022-10-14

围生期解脲支原体感染与不良孕产结局及新生儿疾病关联

李秋平   

  1. 中国人民解放军总医院儿科医学部,中国人民解放军总医院第七医学中心儿科,出生缺陷防控关键技术国家工程实验室,儿童器官功能衰竭北京市重点实验室,北京 100700
  • 作者简介:李秋平(1975-),男,江西人,主任医师,博士生导师,主要研究方向为新生儿疾病。
  • 基金资助:
    国家重点研发计划项目(2021YFC2701700)

Abstract: Perinatal ureaplasma spp. infection is associated with adverse pregnancy outcomes such as infertility, premature rupture of membranes, chorioamnionitis, miscarriage, preterm delivery and even stillbirth, as well as many diseases in neonatal period. This paper will focus on the epidemiological characteristics of ureaplasma spp. infection in perinatal period, the association of ureaplasma spp. exposure with adverse pregnancy outcomes, neonatal and especially preterm related diseases such as sepsis, bronchopulmonary dysplasia, intraventricular hemorrhage and necrotizing enterocolitis, as well as the diagnosis and prevention measures of ureaplasma spp., so as to provide reference for the prevention and treatment of clinically relevant diseases.This paper will focus on the epidemiological characteristics of perinatal Mycoplasma solani infections, the association of perinatal Mycoplasma solani exposure with adverse maternal outcomes, neonatal and especially preterm related diseases such as sepsis, bronchopulmonary dysplasia, intraventricular hemorrhage and necrotizing small bowel colitis, and the diagnostic and preventive measures of Mycoplasma solani for clinical control.

Key words: perinatal period, urealyticum species, newborn, disease

摘要: 围生期解脲支原体感染与不孕不育、胎膜早破、绒毛膜羊膜炎、流产、早产甚至死胎死产等不良妊娠结局及诸多新生儿期疾病存在关联。本文将重点阐述围生期解脲支原体感染的流行病学特点,围生期解脲支原体暴露与不良孕产结局,新生儿尤其是早产儿相关疾病如脓毒症、支气管肺发育不良、脑室内出血和坏死性小肠结肠炎等的关联,以及解脲支原体诊断和防治措施,为临床防治提供参考。

关键词: 围生期, 解脲支原体, 新生儿, 疾病

CLC Number: