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中国临床药理学与治疗学 ›› 2019, Vol. 24 ›› Issue (4): 464-470.doi: 10.12092/j.issn.1009-2501.2019.04.016

• 药物治疗学 • 上一篇    下一篇

电针、中药二法联合盆底肌训练治疗围绝经期妇女压力性尿失禁的临床研究

顾一鸣1,潘弘毅2,盛少琴3,应佳微3,郑丹丹3,姚锦敏1,俞蕾媛3   

  1. 1杭州师范大学医学院,杭州 310018,浙江; 2浙江中医药大学第三临床医学院,杭州 310015,浙江; 3浙江中医药大学附属第二医院妇产科,杭州 310007,浙江
  • 收稿日期:2019-01-09 修回日期:2019-03-12 出版日期:2019-04-26 发布日期:2019-05-01
  • 通讯作者: 盛少琴,女,硕士,主任医师,硕士生导师,主要从事妇产科学研究工作。 Tel:13819195728 E-mail:shshaoqin@sina.com
  • 作者简介:顾一鸣,女,硕士,主要从事妇产科学研究工作。 Tel:18806739222 E-mail:121742945@qq.com
  • 基金资助:

    浙江省中医药科技计划资助项目(2017ZA059)

Clinical study on electroacupuncture and traditional chinese medicine combined with pelvic floor muscle training for stress urinary incontinence in perimenopausal women

GU Yiming 1, PAN Hongyi 2, SHENG Shaoqin 3, YING Jiawei 3, ZHENG Dandan 3, YAO Jinmin 1, YU Leiyuan 3   

  1. 1 Medical College of Hangzhou Normal University, Hangzhou 310018, Zhejiang, China; 2 the third Medical College of Zhejiang Chinese Medical University, Hangzhou 310015, Zhejiang, China; 3 Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310017, Zhejiang, China
  • Received:2019-01-09 Revised:2019-03-12 Online:2019-04-26 Published:2019-05-01

摘要:

目的:探讨电针、中药二法联合盆底肌训练治疗围绝经期妇女压力性尿失禁(stress urinary incontinence,SUI)的疗效。方法:选择2016年10月至2017年9月在浙江中医药大学附属第二医院围绝经期门诊确诊的轻中度SUI患者178例,最终有162例(对照组54例,治疗组1 52例,治疗组2 56例)患者完成治疗及随访。对照组给予Kegel运动训练,治疗组1在对照组的基础上给予电刺激生物反馈治疗,治疗组2进行中医辨证分型后在对照组的基础上给予补中益气汤加减及电针的综合治疗,三组均治疗2个疗程并定期随访6个月;于治疗结束时、结束后3、6个月行1 h尿垫试验、填写国际尿失禁咨询委员会尿失禁问卷简表(ICI-Q-SF),于治疗结束时、结束后6个月行尿动力学检测,并进行疗效评价。结果:三组治疗结束时、结束后3、6个月1 h尿垫试验尿漏量、ICI-Q-SF评分较治疗前明显减少(P<0.05);治疗结束时、结束后6个月腹压漏尿点压力(ALPP)、最大尿道闭合压(MUCP)、膀胱顺应性(BC)较治疗前明显增加(P<0.05);治疗组1、2上述指标改善情况均显著优于对照组(P均<0.05);而治疗组2在1 h尿垫试验尿漏量上的疗效更优于治疗组1(P<0.05),在ICI-Q-SF评分,各项尿动力学指标上的改善与治疗组1无统计学差异(P>0.05)。结论:通过电针、中药二法联合盆底肌训练对于治疗轻中度围绝经期妇女SUI,能减少尿漏量,增加ALPP、MUCP,提高BC,明显改善患者生活质量。

关键词: 压力性尿失禁, Kegel运动训练, 补中益气汤加减

Abstract:

AIM: To explore the effect of electroacupuncture and traditional Chinese medicine combined with pelvic floor muscle training on stress urinary incontinence(SUI)in perimenopausal women. METHODS: 178 patients with mild to moderate SUI were diagnosed in the perimenopausal clinic of the Second Affiliated Hospital of Zhejiang Chinese Medical University from October 2016 to September 2017. Finally, 162 patients completed the treatment and follow-up (Control group n=54, therapy group 1 n=52, therapy group 2 n=56). Kegel exercise training was given to the control group, electrical stimulation biofeedback therapy was given to the therapy group 1 on the basis of the control group. In the therapy group 2, after TCM syndrome differentiation, the treatment of Buzhong Yiqi Decoction and electroacupuncture was given on the basis of the control group. All three groups were treated for 2 courses and regularly followed for 6 months. At the end of treatment, 3 and 6 months after treatment, 1 h urine pad test were performed, and the International Urinary Incontinence Advisory Committee Urinary Incontinence Questionnaire (ICI-Q-SF) were completed. At the end of treatment and 6 months after treatment, urodynamics test were taken, and the efficacy were evaluated. RESULTS:At the end of treatment, 3 and 6 months after treatment, 1 h urine pad test urine leakage and ICI-Q-SF score were significantly lower than those before treatment (P<0.05); at the end of treatment and 6 months after treatment, abdominal pressure leak point pressure (ALPP), maximum urethral closure pressure (MUCP), bladder compliance (BC) significantly increased as compared with before treatment (P<0.05). The improvement of the above indicators in the therapy group 1 and 2 was significantly better than those in the control group (P<0.05), while the therapy group 2 was better than the therapy group 1 in the 1h urine pad test (P<0.05). In the ICI-Q-SF score, various urodynamic indicators, there was no significant difference between therapy group 1 and 2 (P>0.05).CONCLUSION:The combination of electroacupuncture and traditional Chinese medicine combined with pelvic floor muscle training for the treatment of mild to moderate perimenopausal women with SUI can reduce urine leakage, increase abdominal pressure leakage point pressure (ALPP), maximum urethral closure pressure (MUCP), and improve bladder compliance (BC), significantly improve the quality of life of patients.

Key words: stress urinary incontinence, Kegel exercise training, Buzhong Yiqi Decoction

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