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中国临床药理学与治疗学 ›› 1996, Vol. 1 ›› Issue (1): 31-33.

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静滴藻酸双酯钠治疗冠心病的疗效观察

吴铿, 钱卫民1, 吴平1   

  1. 广东医学院附院,湛江 524001
    1广东省人民医院,广州 510600
  • 收稿日期:1996-02-27 修回日期:1996-04-18 出版日期:1996-03-26 发布日期:2020-12-03
  • 作者简介:吴铿,男,31岁,大学本科,主要从事心脏病介入诊断治疗、心血管临床药理工作。饯卫民,男,42岁,博士,研究方向心律失常学,心功能学。

Therapeutic effects of polysaccharide sulfate intravenous injections in treatment of coronary heart disease

Wu Keng, Qian Weiming, Wu Ping   

  1. Affiliated Hospital of Guangdong Medical College, Zhanjian 524001
  • Received:1996-02-27 Revised:1996-04-18 Online:1996-03-26 Published:2020-12-03

摘要: 目的 观察静滴藻酸双酯钠(PSS)治疗32例冠心病患者的疗效。方法 PSS注射液200mg加入10%葡萄糖500ml中静滴,每日1次,14d为疗效;对照组为复方丹参注射液16ml加入10%葡萄糖500ml中静滴,每日1次,14d为1疗程。结果 PSS对心绞痛疗效和复方丹参相近,对心电图、心率、血压、血脂、血流变和心功能的改善均明显优于复方丹参组。结论 PSS对冠心病患者具有明确的疗效。

关键词: 粘多糖类, 冠心病, 血脂, 血流变, 心功能

Abstract: Aim To observe the therapeutic effects of polysaccharide sulfate. Methods Thirty - two patients with coronary heart disease ( M20, F12; age 58±10a) were treated with polysaccharide sulfate 200mg in 10% glucose solution 500ml, iv, drip, qd,for 14d as a courae. For the control group, 16 patients with coronary heart disease (M11, F5; age56±9a) were treated with injection of compound salvia miltiorrhiza 16ml in 10% glucose solution iv, drip, qd, for 14d. Results The efficacy for angina in the polysaccharide sulfate group was similar to that in the compound salvia miltiorrhiza group (90% to 88%), but the EKG, heart rate, pressure blood, blood fat, blood rheology and cardiac function were more significantly improved in the polysaccharide sulfate group than those in the compound salvia miltiorrhiza group(P<0.05). Conclusion Polysaccharide sulfate could have a good effect on the treatment of coronary heart disease.

Key words: Mucoplysaccharide, Coronary heart disease, Blood fat, Blood rheology, Cardiac function

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