关键词: 持续静脉输注, 头孢他啶, 下呼吸道感染

Abstract: Aim This experiment was designed to probe whether low dose (1 g·d^-1)continuous infusion of CAZ is safe, efficacious and low costing in the treatment of infections in low respiratory tract.Methods The patients were divided into control group and treatment group at random.The routine administration (1 g,bid)of CAI was adopted in the treatment group,while the low dose continuous infusion method (1 g·d^-1,and a loading dose 1 g)was used in the control group.Results In the control group and the treatment group, the clinical curative rates were 73.3 % and 73.9%, the efficacy rates were 90.0 % and 91.3 %, the bacterial clearance rates were 86.7 % and 82.7 % and the adverse effect rates were 6.7% and 8.7 % respectively.There was no significant difference between the two groups (P>0.05).Conclusions Low dose continuous infusion of CAZ to treat low respiratory infections is efficacious, safe and economical.

Key words: Key Words: continuous infusion, ceftazidime, low respiratory tract infections