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中国临床药理学与治疗学 ›› 2002, Vol. 7 ›› Issue (3): 237-238.

• 临床研究 • 上一篇    下一篇

解脲支原体对7种抗生素的体外敏感性测定

黄长征, 刘志香, 林能兴, 涂亚庭, 李家文, 张德美   

  1. 华中科技大学同济医学院附属协和医院皮肤科, 武汉 430022
  • 收稿日期:2001-09-20 修回日期:2001-10-18 发布日期:2020-12-01

Susceptibility of ureaplasma urealyticum in vitroto seven antimicrobial agents

HUANG Chang-Zheng, LIU Zhi-Xiang, LIN Neng-Xing, TU Ya-Ting, LI Jia-Wen, ZHANG De-Mei   

  1. Department of Dermatology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022
  • Received:2001-09-20 Revised:2001-10-18 Published:2020-12-01

摘要: 目的: 了解非淋菌性尿道炎(NGU) 患者解脲支原体(UU) 对7 种抗生素的敏感性。方法: 采用微量肉汤稀释法测定体外药物敏感性, 对培养阳性的150 例患者进行了分析。结果: UU 对 7 种抗生素的敏感性的顺序由高到低依次为:交沙霉素(96 6.7 %) 、强力霉素(90.67 %) 、美满霉素(88.67 %) 、司巴沙星(58.67 %) 、 罗 红 霉 素 (39.33 %) 、 氧 氟 沙 星(18.00 %) 和阿奇霉素(8.00 %) 。UU 耐药率最高的为氧氟沙星(31.33 %), 其次为司巴沙星(18.67 %)和罗红霉素(18.00 %) 。结论: UU 存在多重耐药, 对UU 进行药敏监测对指导临床合理用药及防止耐药株的发生有重要意义。

关键词: 解脲支原体, 药物敏感性, 抗生素

Abstract: AIM: To study the susceptibility of ure-aplasma urea1yticum (UU) to 7 antimicrobial agents.METHODS: A specific agent kit was used for UU cul-ture and drug susceptibility detection in vitro.RESULTS: 7 antimicrobial agents on the susceptibility of ureaplasma urea1yticum from high tolow were josamycin (96.67 %), doxycycline (90.67 %), minocyclin (88.67 %), shiba-floxacin (58.67 %), roxithromycin (39.33 %), ofloxacin (18.00 %), and azithromycin (8.00 %), respectively.The higher rates of drug resis-tance of UU were ofloxacin (31.33 %), shibafloxacin (18.67 %), and roxithromycin (18.00 %), respective-ly.CONCLUSION: UU shows multiple drug resistance. The determination of the susceptibility of UU to antimicro-bial agents can instruct reasonable medication and prevent the occurrence of drug resistance.

Key words: ureaplasma urea1yticum, drug suscepti-bility, antibiotic agents

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