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中国临床药理学与治疗学 ›› 2002, Vol. 7 ›› Issue (4): 302-305.

• 基础研究 • 上一篇    下一篇

芦丁铬对正常和高血脂大鼠血脂的调节作用

刘祎春, 刘钢   

  1. 宁夏大学化学化工学院, 银川 750021
  • 收稿日期:2002-03-11 修回日期:2002-04-10 出版日期:2002-08-26 发布日期:2020-11-24
  • 通讯作者: 刘祎春, 女, 讲师, 硕士。主要从事天然产物分离提取及药理研究。Tel:0951-2062889 E-mai l:liuyc @nxu. edu. cn
  • 基金资助:
    1 本课题是宁夏大学科学研究基金资助项目(№003101)

Effects of chromium rutin on metabolism of blood lipid in rats

LIU Yi-Chun, LIU Gang   

  1. College of Chemistry &Chemical Engineering, Ningxia University, 750021, Yinchuan
  • Received:2002-03-11 Revised:2002-04-10 Online:2002-08-26 Published:2020-11-24

摘要: 目的: 研究芦丁与三价铬离子生成的芦丁铬络合物(芦丁铬)调节血脂作用。方法: 采用大鼠高血脂模型, 观察芦丁铬对正常和高血脂大鼠的甘油三酯、胆固醇、HDL-胆固醇和LDL-胆固醇浓度的影响。结果: 芦丁铬能有效地升高正常和高血脂大鼠血铬水平, 降低血清甘油三酯浓度;升高高血脂大鼠血清高密度脂蛋白水平;对高血脂大鼠血清总胆固醇和低密度脂蛋白也有降低趋势。结论: 芦丁铬对正体和高血脂大鼠的血脂均有调节作用。

关键词: 芦丁铬, 微量元素, 血铬, 血脂

Abstract: AIM: To study the effects of chromium rutin synthesized with rutin and chromium (Ⅲ) on metabolism of blood lipid. METHODS: The effects of chromium rutin on metabolism of blood lipid were evaluated by the changes of triglyceride, cholesterol, HDLcholesterol, and LDL-cholesterol in normal rats and the rats with high blood lipid. RESULTS: Chromium rutin could increase the blood chromium, decrease the concentrations of triglyceride, cholesterlo and LDL-cholestelol, and increase the concentration of HDL-cholesterol in normal and the rats with high blood lipid rats. CONCLUSION: Chromium rutin has an effect on the blood lipid in rats.

Key words: chromium rutin, trace-elements, blood chromium, blood Lipid

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