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中国临床药理学与治疗学 ›› 2003, Vol. 8 ›› Issue (2): 210-212.

• 研究原著 • 上一篇    下一篇

复方丹参与黄芪联合治疗慢性肺心病急性发作期的疗效评价

刘鑫   

  1. 商丘市第一人民医院急诊科, 商丘 476100, 河南
  • 收稿日期:2002-11-01 修回日期:2002-12-06 出版日期:2003-04-26 发布日期:2020-11-25
  • 通讯作者: 刘鑫, 女, 学士, 主治医师, 主要从事内科急诊工作。Tel:0370-3213131

Curative effect of salvia miltiorrhiza compound and astragali on exacerbating chronic cor pulmonale

LIU Xin   

  1. Department of Emergency Medicine, Shangqiu First People's Hospital, Shangqiu 476100, Henan
  • Received:2002-11-01 Revised:2002-12-06 Online:2003-04-26 Published:2020-11-25

摘要: 目的: 探讨复方丹参和黄芪联合治疗慢性肺心病急性发作期的临床疗效。方法: 115 例病人随机分为两组, 常规治疗组(56 例) 给予氧疗、改善通气、控制感染、祛痰、平喘等常规治疗。丹参黄芪组(59 例) 在常规治疗的基础上加用复方丹参、黄芪。结果: 经过治疗, 丹参黄芪组显效率为57.6%, 总有效率为98.3%;常规治疗组则显效率为33.9%, 总有效率为89.3%(P <0.05)。结论: 复方丹参和黄芪联合治疗可改善慢性肺心病急性发作期的血液微循环障碍, 降低肺动脉高压, 改善心肺功能。

关键词: 药效学, 肺心病, 复方丹参, 黄芪

Abstract: AIM: To study the effects of salvia miltiorrhiza compound and astragali in the treatment of patients with exacerbating chronic cor pulmonale. METHODS: 115 cases were randomly divided into two groups, with 56 cases in routine treatment group and 59 cases in salvia miltiorrhiza and astragali group.Besides routine treatment, such as oxygen therapy, ventilation improvement, administration of antibiotics, expectorant, and antiasthma, the patients in salvia miltiorrhiza and astragali group were treated with salvia miltiorrhiza compound and astragali, while subjects in routine treatment group were treated with routine therapy only. RESULTS: After treatment, the highly effective rates of two groups were 57.6% and 33.9%, and total effective rates were 98.3% and 89.3%, respectively.The therapeutic effect was significantly different (P <0.05) between the two groups. CONCLUSION: Salvia miltiorrhiza compound and astragali can improve the microcirculation and lower the pulmonary artery pressure and improve heart and lung function.

Key words: pharmacodynamics, cor pulmonale, salvia miltiorrhiza compound, astragali

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