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中国临床药理学与治疗学 ›› 2003, Vol. 8 ›› Issue (3): 351-353.

• 研究原著 • 上一篇    下一篇

阿拓莫兰治疗病毒性肝炎的临床研究

栾玲, 张经良1   

  1. 淄博市第四人民医院传染科三科, 1药剂科, 淄博 255067, 山东
  • 收稿日期:2002-10-30 修回日期:2003-01-03 出版日期:2003-06-26 发布日期:2020-11-25
  • 通讯作者: 栾玲, 女, 主治医师, 现从事传染病临床工作。Tel:13515333896

Clinical efficacy of atomolan in treatment of the patients with virus hepatitis

LUAN Ling1, ZHANG Jing-Liang   

  1. Department of Infectious Disease, 1Department of Pharmacy, The Fourth People's Hospital of Zibo, Zibo 255067, Shandong
  • Received:2002-10-30 Revised:2003-01-03 Online:2003-06-26 Published:2020-11-25

摘要: 目的: 探讨阿拓莫兰治疗病毒性肝炎的疗效及不良反应。方法: 选择96 例病毒性肝炎患者, 随机分成治疗组和对照组, 其中对照组46例, 采用综合基础治疗;治疗组50 例, 在综合基础治疗的基础上, 加用阿拓莫兰1.8 g·d-1, 10%GS 250 ml, ivgtt, 1mon 为1疗程, 治疗2 ~ 3 个疗程。结果: 疗程结束时, 治疗组在临床症状、体征改善方面, 以及在肝功能的改善方面均优于对照组, 治疗组的总有效率为90.0 %, 而对照组的总有效率为54.3 %, 有显著的统计学意义(P <0.01), 未见严重的药物不良反应。结论: 阿拓莫兰治疗病毒性肝炎有确切疗效, 且无毒副作用, 值得在临床推广使用。

关键词: 药效学, 阿拓莫兰, 病毒性肝炎, 不良反应

Abstract: AIM: To observe clinical efficacy of atomolan in treatment of the patients with virus hepatitis. METHODS: 96 patients were randomly divided into 2 groups.46 patients as a control group were given conventional treatment.50 patients as a treatment group were administered atomolan 1.8 g·d -1 iv gtt for 1mon on base of conventional treatment. RESULTS: After the therapy, the clinical symptoms and liver function in the treatment group was improved than that in the control group.The general effect was 90.0 % and 54.3 % in 2 groups.Side effects had not been found. CONCLUSION: Atomolan is an effective agent in treatment of the patients with virus hepatitis.

Key words: phaemacodynamics, atomolan, virus hepatitis, side effects

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