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中国临床药理学与治疗学 ›› 2004, Vol. 9 ›› Issue (6): 713-716.

• 研究原著 • 上一篇    下一篇

刺五加注射液对小鼠急性心肌缺氧的保护作用

许善初, 陶明飞1   

  1. 蚌埠医学院附属医院药剂科, 1机能实验中心, 蚌埠233003, 安徽
  • 收稿日期:2004-03-02 修回日期:2004-04-01 发布日期:2020-11-22
  • 通讯作者: 许善初, 男, 主管药师, 研究方向:药理学和药剂学研究。Tel:0552-3064590-2346 E-mai l:vi ctory6314 @vip.sina.com

Protective effect of Acanthopanecis senticosus injection in rats with acute myocardial hypoxia

XU Shan-Chu, TAO Ming-Fei1   

  1. Department of Pharmacy, Affiliated Hospital; 1Function Experimental Centre, Bengbu Medical College, Bengbu 233003,Anhui, China
  • Received:2004-03-02 Revised:2004-04-01 Published:2020-11-22

摘要: 目的 观察刺五加对小鼠急性心肌缺氧的保护作用。 方法 常压和低压缺氧条件下分别观察小鼠平均存活时间和心肌耗氧量。 结果 刺五加注射液高低剂量组均可使小鼠常压和低压条件下平均存活时间延长;降低常压、低压条件下心肌耗氧量。 结论 刺五加注射液能明显降低小鼠心肌氧耗, 提高小鼠抗应激能力, 保护缺氧心肌。

关键词: 刺五加, 心肌缺氧, 抗应激, 小鼠

Abstract: AIM: To observe the protective effect of Acanthopanecis senticosus injection in rats with acute myocardial hypoxia. METHODS: The mean survival time and capacity for myocardial oxygen consumption were detected in rats with acute hypoxia under ordinary or low pressure. RESULTS: Various dosages of Acanthopanecis senticosus injection could prolong the mean survival time and reduce capacity for myocardial oxygen consumption in rats with acute hypoxia under ordinary or low pressure. CONCLUSION: The Acanthopanecis senticosus injection can evidently reduce capacity for myocardial oxygen consumption and increase ability to anti-stress and plays a protective role in rats with hypoxic myocardium.

Key words: Acanthopanecis senticasi, myocardial hypoxia, anti-stress, rats

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