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中国临床药理学与治疗学 ›› 2005, Vol. 10 ›› Issue (11): 1201-1209.

• 综述 •    下一篇

抗癫痫药物研究进展

洪钢, 章江1, 王琳辉2   

  1. 江苏省药品认证管理中心,南京 210002,江苏;
    1康恩贝集团有限公司,杭州 310052,浙江;
    2苏州大学医学院生理学教研室,苏州 215007,江苏
  • 收稿日期:2005-08-10 修回日期:2005-09-19 出版日期:2005-11-26 发布日期:2020-11-12

Progresses in studies on anti-epileptic drugs

HONG Gang, ZHANG Jiang-sheng1, WANG Lin-hui2   

  1. Centre forDrug Certification of Jiangsu,Nanjing 210002,Jiangsu,China;
    1Conba GrouPCo.Ltd.,Hangzhou 310052,Zhejiang,China;
    2Department of Physiology School of Medicine of Soochow University,Suzhou 215007,Jiang-su,China
  • Received:2005-08-10 Revised:2005-09-19 Online:2005-11-26 Published:2020-11-12

摘要: 癫痫是一种由多种不同原因引起的严重脑部疾病,随着对癫痫发病机理研究的深入,更多的抗癫痫药物得以开发使用。本文分类综述了γ-氨基丁酸(GABA)能药物、谷氨酸受体拮抗剂以及作用于膜离子通道、神经肽受体等靶点的抗癫痫新药。

关键词: 癫痫, γ-氨基丁酸受体, 谷氨酸受体, 离子通道, 神经肽

Abstract: Epilepsy is a common serious brain disor-derand comprises a wide range of symptom induced by varying etiologies.As more and more knowledge of mech-anisms underlying seizure propagation of epilepsy gained,much more new antiepileptic-drug has been developed.In this article,we reviewed some kinds of new antiepileptic drugs used orresearched in recent years.

Key words: epilepsy, GABA-receptor, glutamate receptor, ion channel, neuropeptide

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