氯吡格雷在经皮冠状动脉介入术围手术期中的应用现状

中国临床药理学与治疗学 ›› 2007, Vol. 12 ›› Issue (12): 1354-1358.

氯吡格雷在经皮冠状动脉介入术围手术期中的应用现状

吴辉, 杨俊, 丁家望, 李稳慧, 李松, 李莉

三峡大学第一临床医学院＆宜昌市中心人民医院心血管内科,宜昌 443003,湖北

收稿日期:2007-08-20 修回日期:2007-10-29 发布日期:2020-11-10
通讯作者: 杨俊,男,教授,硕导,研究方向:心血管疾病的基础与临床。Tel:0717-6486177 E-mail:yangjun@medmail.com.cn
作者简介:吴样,男,硕士,医师,研究方向:心血管疾病的基础与临床。Tel:15871618672 E-mail:caniiology_wh@l26.com

Application status of using clopidogrel during perioperative period of percutaneous coronary intervention

WU Hui, YANG Jun, DING Jia-wang, Ll Wen-hui, Ll Song, Ll Li

Department of Cardiology, First College of Clinical Medical Science, China Three Gorges University & Yichang Central People's Hospital, Yichang 443003, Hubei, China

Received:2007-08-20 Revised:2007-10-29 Published:2020-11-10

摘要/Abstract

摘要： 经皮冠状动脉介入术(PCI) 己广泛应用于临床,但术后支架内血栓形成及再狭窄等并发症影响了其远期疗效。血小板激活是 PCI 围手术期血栓形成过程中最关键的环节。氯吡格雷作为有效的抗血小板药物之一,近年来多个大规模临床试验已经逐渐确立了其在 PCI 围手术期中应用的地位。

关键词: 氯吡格雷, 经皮冠状动脉介入术, 再狭窄, 支架内血栓形成

Abstract: Percutaneous coronary intervention(PCI) has become one of the most important therapeutic methods for atherosclerotic heart disease(AHD), but the following complications such a-, stent thrombosis and restenosis affected its long-term efficacy. Platelet activation was a key component of thrombosis of during perioperative period PCI. As one of the most effective anti platelet drugs, clo-pidogrel has been established its important role in preventing thrombosis during perioperative period of PCI. After several large-scale clinical trials in recent years.

Key words: clopidogrel, percutaneous coronarγ intervention, restenosis, stent thrombosis

中图分类号:

R541

吴辉, 杨俊, 丁家望, 李稳慧, 李松, 李莉. 氯吡格雷在经皮冠状动脉介入术围手术期中的应用现状[J]. 中国临床药理学与治疗学, 2007, 12(12): 1354-1358.

WU Hui, YANG Jun, DING Jia-wang, Ll Wen-hui, Ll Song, Ll Li. Application status of using clopidogrel during perioperative period of percutaneous coronary intervention[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2007, 12(12): 1354-1358.

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