复方青黄胶囊治疗慢性粒细胞白血病6 例临床报道

中国临床药理学与治疗学 ›› 2007, Vol. 12 ›› Issue (4): 478-480.

• 短篇报道 • 上一篇

复方青黄胶囊治疗慢性粒细胞白血病6 例临床报道

唐强¹, 沈杰², 刘昭前²

¹湖南省怀化医学高等专科学校附属医院暨怀化市第三人民医院药剂科, 怀化418000, 湖南;
²中南大学湘雅医学院临床药理研究所, 长沙410078, 湖南

收稿日期:2007-01-15 修回日期:2007-01-15 发布日期:2020-10-30
作者简介:唐强, 男, 副教授, 硕士在读, 主要从事临床药学研究。Tel:13037459681 E-mail:tangqiang9681 @sina.com
基金资助:
教育部“ 留学回国人员科研启动基金” (教外司留[2005] 383 号)

Case reports on 6 patients with chronic myelocytic leukemia treated with complex capsules of Qinghuang

TANG Qiang¹, SHEN Jie², LIU Zhao-qian²

¹Department of Pharmacy, the Affiliated Hospital of Huaihua Medical Training School, Huaihua 418000, Hunan, China;
²Institute of Clinical Pharmacology, Central South University Xiangya School of Medicine, Changsha 410078, Hunan,China

Received:2007-01-15 Revised:2007-01-15 Published:2020-10-30

摘要/Abstract

摘要： 目的研究复方青黄胶囊对慢性粒细胞白血病的临床疗效。方法采用青黛、雄黄等制备成中药复方胶囊, 进行临床慢性粒细胞白血病志愿者服药治疗研究, 观察复方青黄胶囊对患者治疗前后血象及对预后和生存的影响。结果 6 例患者均获得完整的随访资料, 接受复方青黄胶囊治疗的慢性粒细胞白血病患者4 例完全缓解, 2 例部分缓解;6 例患者均未出现急性病变, 1 例已存活16 年。结论复方青黄胶囊对慢性粒细胞白血病有较好治疗效果,且副作用少, 为中药砷剂治疗慢性粒细胞白血病提供了临床参考。

关键词: 复方青黄胶囊, 慢性粒细胞白血病, 青黛, 雄黄

Abstract: AIM: To investigate the clinical effects of complex capsules of Qinghuang in the treatment of patients with chronic myelocytic leukemia (CML). METHODS: The complex capsules of Qinghuang are composed of indigo naturalis, realgar, etc.The volunteers with chronic myelocytic leukemia received the clinical therapy of complex capsules of Qinghuang.The analysis of hemogram and evaluation of survival and prognosis in patients treated with and without complex capsules of Qinghuang were observed. RESULTS: We got the entire information and data of follow-up visit of patients after they were treated with complex capsules of Qinghuang for a long time.Among 6 patients, 4 of them were complete remission (CR) and 2 were partial remission (PR), and 1 patient had survived for 16 years.All patients did not deteriorate into acute transformation phase. CONCLUSION: The complex capsules of Qinghuang have a good therapeutic efficacy on the treatment of patients with chronic myelocytic leukemia, and they have only some gentle side effects.The present study provides some clinical evidences for the treatment of CML with traditional Chinese medicine and arsenical in the future.

Key words: complex capsules of Qinghuang, chronic myelocytic leukemia, indigo naturalis, realgar

中图分类号:

R965
R730.5

唐强, 沈杰, 刘昭前. 复方青黄胶囊治疗慢性粒细胞白血病6 例临床报道[J]. 中国临床药理学与治疗学, 2007, 12(4): 478-480.

TANG Qiang, SHEN Jie, LIU Zhao-qian. Case reports on 6 patients with chronic myelocytic leukemia treated with complex capsules of Qinghuang[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2007, 12(4): 478-480.

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复方青黄胶囊治疗慢性粒细胞白血病6 例临床报道

Case reports on 6 patients with chronic myelocytic leukemia treated with complex capsules of Qinghuang

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