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中国临床药理学与治疗学 ›› 2008, Vol. 13 ›› Issue (7): 786-791.

• 定量药理学 • 上一篇    下一篇

冠心病心绞痛(气虚血瘀证)症状疗效评分量表的研究

吕映华, 何迎春, 杨娟, 许羚, 刘红霞, 郑青山   

  1. 上海中医药大学药物临床研究中心, 上海市高校E研究院, 上海 201203
  • 收稿日期:2008-05-05 修回日期:2008-05-29 出版日期:2008-07-26 发布日期:2020-10-14
  • 通讯作者: 郑青山,男,博士,教授,博士生导师,研究方向:临床药理学与生物统计学。Tel:021-51323006 E-mail:zhengqs11@21cn.com
  • 基金资助:
    上海市教委重点学科项目(J50303);上海市重点学科建设项目(Y0302);国家科技支撑计划项目(2006BAI08B04-7);上海市高校E研究院项目(E0308)

Study of the symptoms scale for evaluating changes in patients with coronary angina pectoris and Qi-deficiency combined with stagnation of blood in traditional Chinese medicine

LV Ying-hua, HE Ying-chun, YANG Juan, XU Ling, LIU Hong-xia, ZHENG Qing-shan   

  1. Center for Drug Clinical Research, Shanghai University of Traditional Chinese Medicine, E-Institute of Shanghai University, Shanghai 201203, China
  • Received:2008-05-05 Revised:2008-05-29 Online:2008-07-26 Published:2020-10-14

摘要: 目的:建立冠心病心绞痛(气虚血瘀证)症状疗效评分量表。方法:症状评分与其发生率(频率)、重要性(专家评定)及严重性(轻中重)有关,根据以上3种因素(因子)的症状评分数学模型,形成冠心病心绞痛(气虚血瘀证)中医症状的评分量表,通过信度、效度、反应度的评价,确认其可行性和合理性。结果:6个症状(胸痛、胸闷、心悸、气短、神疲乏力、唇色紫暗)作为疗效评分症状群,根据其发生率、重要性和严重性确定了各自权重因子和量表等级分值。信度结果可靠,一致性良好,反应灵敏。结论:冠心病心绞痛(气虚血瘀证)中医症状疗效评分量表,可为此类临床研究提供一个应用工具。

关键词: 冠心病, 心绞痛, 气虚血瘀证, 量表, 信度, 效度, 反应度, 权重因子

Abstract: AIM: To develope a symptom scale for evaluating efficacy of coronary angina pectoris and Qideficiency combined with stagnation of blood.METHODS: The symptom score is always related with its incidence rate (frequency), its importance (evaluated by experts)and its serious degree (light, moderate and serious) in a measuring scale, and a mathematical model was used to calculate the weight factor and its score for each symptom in the scale.In an example of coronary angina pectoris and Qi-deficiency combined with stagnation of blood trial was analyzed based on the scale, and the scale was evaluated with the reliability, the validity, and the responsibility to change.RESULTS: Six symptoms (chest pain, chest distress, palmus, short breath, debilitation, and cyanosis)were selected as indices, and their weight factors and grades were calculated in a score scale.Some evaluations demonstrated that the approach showed a better feasibility, uniformity, and responsibility to change.CONCLUSION: This scale can be used to evaluating the efficacy of coronary angina pectoris and Qi-deficiency combined with stagnation of blood in traditional Chinese medicine.

Key words: coronary artery disease, angina pectoris, Qi-deficiency combined with stagnation of blood, scale, reliability, validity, responsibility to change, weight factor

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