高原地区碳酸利多卡因在剖宫产术中的临床应用

中国临床药理学与治疗学 ›› 2008, Vol. 13 ›› Issue (8): 922-925.

高原地区碳酸利多卡因在剖宫产术中的临床应用

陈晓光¹, 吕宏大¹, 尚安云², 郭宝琛¹

¹解放军总医院第一附属医院麻醉科, 北京100037;
²解放军第22医院麻醉科, 格尔木816000, 青海

收稿日期:2008-06-04 修回日期:2008-07-02 出版日期:2008-08-26 发布日期:2020-10-12
作者简介:陈晓光, 男, 主治医师, 研究方向:麻醉药理学。Tel:010-66848070　E-mail:porscheat@163.com

Clinical application of lidocaine carbonation on cesarean section in plateau area

CHEN Xiao-guang¹, LV Hong-da¹, SHANG An-yun², GUO Bao-chen¹

¹Department of Anesthesiology, First Affiliated Hospital of PLA General Hospital, Beijing 100037, China;
²Department of Anesthesiology of 22th Hospital of PLA, Ge'ermu 816000, Qinghai, China

Received:2008-06-04 Revised:2008-07-02 Online:2008-08-26 Published:2020-10-12

摘要/Abstract

摘要： 目的:比较在高原地区不同麻醉方法用于剖宫产手术的麻醉效果及安全性。方法:选择60例行剖宫产手术患者,ASA I～II级, 随机分为2%盐酸利多卡因组(I组, 选择L1～2间隙行硬膜外穿刺向上置管3～4cm), 1.73%碳酸利多卡因组(II组, 麻醉穿刺方法同I组)和0.5%布比卡因重比重溶液组(III组, 选择L3～4间隙穿刺行腰硬联合阻滞)三组。比较三组间麻醉起效时间、麻醉完善时间、麻醉最高平面, 胎儿娩出时间, 记录麻醉对患者血压、心率的影响及患者的不良反应。结果:II组与I组比较麻醉起效快, 麻醉完善时间短, 胎儿娩出时间短;与III组比较对患者心率、血压影响小, 患者不良反应少, 差异有统计学意义。结论:高原地区低氧环境下在剖宫产手术中用碳酸利多卡因行硬膜外麻醉具有麻醉起效快、麻醉完善时间短、效果确切的特点, 而且对患者血流动力学影响小, 不良反应少, 提高了母婴术中安全性,是一种更为安全、可靠的麻醉方法。

关键词: 碳酸利多卡因, 剖宫产术, 高原地区

Abstract: AIM:To compare the effect and safety of different epidural anesthesia methods on cesarean section in plateau area.METHODS:Sixty ASA I-IIpatients undergone cesarean section were randomly allocated into three groups :lidocaine hydrochloride group (group Ⅰ, epidural anesthesia with 2% lidocaine hydrochloride), lidocaine carbonation group(group Ⅱ, epidural anesthesia with 1.73% lidocaine carbonation), and bupivacaine group(group Ⅲ, spinal anesthesia with 0.5% hyperbaric bupivacaine).The anaesthesia onset time, consummate time, highest plane, and fetal disengagement time of three groups were compared.The blood pressure, heart rate, adverse reaction of patients in each group were recorded.RESULTS: Compared with group Ⅰ, group Ⅱhad faster anaesthesia onset time, shorter consummate time and fetal disengagement time.Compared with group III, group Ⅱ had less adverse reaction and less effect on blood pressure and heart rate of patients, there were significant difference.CONCLUSION:Epidural anesthesia with lidocaine carbonation on cesarean section in plateau hypoxia circumstances has the characteristics of faster anaesthesia onset time, shorter anaesthesia consummate time and exact effect, and moreover, it has less effect of haemodynamics and adverse reaction and it can elevate safety in parturient and neonate operation.Therefore, it is a safe and reliable anaesthesia method for cesarean section in plateau area.

Key words: lidocaine carbonation, cesarean section, plateau area

中图分类号:

R614

陈晓光, 吕宏大, 尚安云, 郭宝琛. 高原地区碳酸利多卡因在剖宫产术中的临床应用[J]. 中国临床药理学与治疗学, 2008, 13(8): 922-925.

CHEN Xiao-guang, LV Hong-da, SHANG An-yun, GUO Bao-chen. Clinical application of lidocaine carbonation on cesarean section in plateau area[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(8): 922-925.

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