血液稀释对肌松药作用影响的研究进展

中国临床药理学与治疗学 ›› 2010, Vol. 15 ›› Issue (3): 356-360.

• 综述与讲座 • 上一篇

血液稀释对肌松药作用影响的研究进展

袁晓红¹, 郭建荣¹, 金孝岠²

¹宁波大学医学院附属李惠利医院麻醉科, 宁波 315040,浙江;
²皖南医学院附属弋矶山医院麻醉科,芜湖 241001,安徽

收稿日期:2010-02-20 修回日期:2010-03-16 发布日期:2020-10-14
通讯作者: 郭建荣,男,博士后,教授,主任医师,硕士生导师,研究方向:麻醉生理与药理学研究。Tel: 0574-87018725 E-mail: Jianrguo@126.com
作者简介:袁晓红,女,在读硕士研究生,研究方向:全麻与应激。Tel: 0574-87018726 E-mail: xiaohong123045@yahoo.cn
基金资助:
宁波市优秀中青年卫生技术人才基金(200856)

Progress of Hemodilution on the role of muscle relaxant effects

YUAN Xiao-hong¹, GUO Jian-rong¹, JIN Xiao-ju²

¹Department of Anesthesiology, Lihuili Hospital, Medical School of Ningbo University,Ningbo 315040,Zhejiang,China;
²Department of Anesthesiology,Yijishan Hospital of Wannan Medical College, Wuhu 241001,Anhui,China

Received:2010-02-20 Revised:2010-03-16 Published:2020-10-14

摘要/Abstract

摘要： 血液稀释(HD)是术中常用的减少自体血丧失和异体血输注的血液保护方法,但血液稀释常会引起血流动力学、血液成分和机体内环境的变化,从而对麻醉中所用麻醉药物尤其是肌松药的药效学和药动学会产生一定的影响。

关键词: 血液稀释, 肌松药, 药动学, 药效学

Abstract: Hemodilution (HD) is a commonly blood conservation method that used to reduce autologous blood loss and allogeneic blood transfusion during operation,but it often causes changes of hemodynamics,blood components and internal environment,resulting in anesthetic drugs appearing some impact of pharmacodynamics and pharmacokinetics,especially muscle relaxants.In this article,the progress of hemodilution on the role of muscle relaxants effects is reviewed.

Key words: Hemodilution, Muscle relaxants, Pharmacokinetics, Pharmacodynamics

中图分类号:

R614

袁晓红, 郭建荣, 金孝岠. 血液稀释对肌松药作用影响的研究进展[J]. 中国临床药理学与治疗学, 2010, 15(3): 356-360.

YUAN Xiao-hong, GUO Jian-rong, JIN Xiao-ju. Progress of Hemodilution on the role of muscle relaxant effects[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(3): 356-360.

参考文献

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血液稀释对肌松药作用影响的研究进展

Progress of Hemodilution on the role of muscle relaxant effects

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