草分支杆菌注射液联合苄星青霉素治疗早期梅毒的疗效分析

中国临床药理学与治疗学 ›› 2011, Vol. 16 ›› Issue (1): 82-84.

草分支杆菌注射液联合苄星青霉素治疗早期梅毒的疗效分析

王军, 刘雯蓓, 慈超, 常小丽, 汪丽, 杭守云, 季必华

皖南医学院弋矶山医院皮肤性病科,芜湖 241001,安徽

收稿日期:2010-12-12 修回日期:2011-01-20 发布日期:2020-09-16
通讯作者: 季必华,男,硕士生导师,主任医师,副教授,研究方向:性传播疾病。
作者简介:王军,男,硕士,主治医师,讲师,主要研究方向为皮肤性病学。E-mail: 1813wj@163.com
基金资助:
皖南医学院弋矶山医院青年骨干医师基金

Efficacy analysis of Mycobacterium phlei combined with benzathine penicillin in the treatment of early syphilis

WANG Jun, LIU Wei-bei, CI Chao, CHANG Xiao-li,WANG Li,HANG Shou-yun,JI Bi-hua

Department of Dermatology, Yijishan Hospital of Wannan Medical College, Wuhu 241001,Anhui,China

Received:2010-12-12 Revised:2011-01-20 Published:2020-09-16

摘要/Abstract

摘要： 目的: 探讨草分支杆菌注射液联合苄星青霉素在早期梅毒治疗中的作用。方法: 将80例早期梅毒患者分为治疗组(草分支杆菌注射液联合苄星青霉素)和对照组(单用苄星青霉素),观察时间6个月。结果: 治疗3、6个月时治疗组快速血浆反应素试验(RPR)几何平均滴度低于对照组(P<0.05),治疗6个月治疗组RPR阴转率为40%,对照组为 21.2%,两者差异有统计学意义(P<0.05)。结论: 草分支杆菌注射液辅助治疗早期梅毒可以增强苄星青霉素驱梅的疗效。

关键词: 草分支杆菌, 苄星青霉素, 早期梅毒

Abstract: AIM: To investigate the effects of Mycobacterium Phlei combined with benzathine penicillin in the treatment of early syphilis.METHODS: Eighty cases of early syphilis were divided into treatment group (Mycobacterium phlei combined with Benzathine penicillin) and control group (benzathine penicillin alone), all the patients were observed for 6 months.RESULTS: The geometric mean titers of rapid plasma reagin test (RPR) in the treatment group at the 3th and 6th months were lower than those in the control group (P<0.05). The RPR negative conversion rate was 40% after 6 months in treatment group, while 21.2% in the control group, the difference was significant (P<0.05).CONCLUSION: Mycobacterium Phlei can enhance the efficacy of benzathine penicillin in the treatment of early syphilis.

Key words: Mycobacterium Phlei, Benzathine penicillin, Early syphilis , , , ,

中图分类号:

R759.1

引用本文

王军, 刘雯蓓, 慈超, 常小丽, 汪丽, 杭守云, 季必华. 草分支杆菌注射液联合苄星青霉素治疗早期梅毒的疗效分析[J]. 中国临床药理学与治疗学, 2011, 16(1): 82-84.

WANG Jun, LIU Wei-bei, CI Chao, CHANG Xiao-li,WANG Li,HANG Shou-yun,JI Bi-hua. Efficacy analysis of Mycobacterium phlei combined with benzathine penicillin in the treatment of early syphilis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2011, 16(1): 82-84.

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