关键词: 罗哌卡因, 芬太尼, 连续髂筋膜腔隙阻滞, 术后镇痛, 小儿

Abstract: To investigate the analgesic effect and safety of continuous fascia iliaca compartment blockade with ropivacaine combined with fentanyl for postoperative pain control in femoral fracture children. METHODS: 60 children with femoral fracture, American Society of Anesthesiologists physical status I or II, were enrolled in this study. The patients were divided randomly into two groups, which received patient-controlled analgesia at the end of operation for 48 hours. Group I was given intravenous fentanyl only, and Group F was given continuous fascia iliaca compartment blockade with ropivacaine combined with fentanyl.Any children with pain score > 3 were administered with a bolus injection (“press”). The vital signs( HR, RR, BP), SpO2 , score of pain and sedation, degree of satisfaction, frequency of press, adverse reactions were recorded postoperatively at 0.5,1,2,4, 8,12,24 h and 48 h. RESULTS: Compared with Group I,the pain score of Group F was lower at 0.5,1,2,4,8 h and 12 h (P<0.05);the sedation score of Group F was lower at all time points (P<0.05);the times of press of Group F was lower (P<0.05);the incidence of nausea and vomiting in Group F was lower (P<0.05). CONCLUSION: Continuous fascia iliaca compartment blockade with ropivacaine combined with fentanyl is safe and reduces the incidence of postoperative adverse reactions,providing better postoperative pain control in femoral fracture children.

Key words: ropivacaine, fentanyl, continuous fascia iliaca compartment blockade, postoperative analgesia, children