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中国临床药理学与治疗学 ›› 2014, Vol. 19 ›› Issue (4): 465-469.

• 综述与讲座 • 上一篇    下一篇

管腔型乳腺癌研究进展

蒋艳1, 张帆2   

  1. 1皖南医学院临床医学系,芜湖 241001,安徽;
    2皖南医学院弋矶山医院病理科,芜湖 241001,安徽
  • 收稿日期:2013-12-13 修回日期:2014-03-31 出版日期:2014-04-26 发布日期:2020-07-24
  • 通讯作者: 张帆,通信作者,男,硕士生导师、副教授,研究方向:妇科及乳腺肿瘤病理学。Tel:0553-5739792 E-mail:zhangfan401401@aliyun.com
  • 作者简介:蒋艳,女,硕士研究生,医师,研究方向:乳腺肿瘤病理学。Tel:0553-3996177 E-mail:117504434@qq.com

Advances in luminal breast cancer

JIANG Yan1, ZHANG Fan2   

  1. 1Department of Clinical Medicine, Wannan Medical College, Wuhu 241001, Anhui, China;
    2Department of Pathology, Yijishan Hospital of Wannan Medical Gollege, Wuhu 241001, Anhui, China
  • Received:2013-12-13 Revised:2014-03-31 Online:2014-04-26 Published:2020-07-24

摘要: 利用免疫组化技术对乳腺癌从基因水平上加以分型,不仅能够判断肿瘤的预后,还能够预测肿瘤对治疗的反应,为肿瘤的个体化治疗提供依据。本文以管腔型乳腺癌为研究方向,从六个方面进行论述:管腔型乳腺癌的认识过程;管腔型乳腺癌的形态特征;管腔型乳腺癌的免疫表型;管腔型乳腺癌的基因表达;管腔型乳腺癌的分子遗传学;管腔型乳腺癌的临床特点及预后,为管腔型乳腺癌的进一步研究提供依据。

关键词: 乳腺癌, 管腔型, 免疫组化, Her-2

Abstract: We use the immunohistochemical techniques to be parting from breast cancer at the genetic level, not only to determine the prognosis of the tumor, but also be able to predict tumor response to treatment, provide the basis for individualized treatment of cancer. In this study, the research direction of luminal breast cancer, from six aspects discussed: the process of luminal breast cancer awareness; molecular luminal breast cancer; morphological features of luminal breast cancer; luminal breast cancer immune phenotype; gene expression of luminal breast cancer genetics; clinical features and prognosis of luminal breast cancer, providing a basis for further study of luminal breast cancer.

Key words: breast cancer, luminal like, immunohistochemical, human epidermal growth factor receptor 2

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