基于Bland-Altman法对定量资料的一致性评价及其SAS宏实现

中国临床药理学与治疗学 ›› 2014, Vol. 19 ›› Issue (8): 898-903.

基于Bland-Altman法对定量资料的一致性评价及其SAS宏实现

倪平¹, 陈卉¹, 涂娇¹, 许林勇²

¹ 中南大学公共卫生学院卫生统计学教研室,长沙 410078,湖南;
² 中南大学湘雅三医院药物临床研究统计分析中心,长沙 410013,湖南

收稿日期:2014-04-21 修回日期:2014-07-18 出版日期:2014-08-26 发布日期:2014-08-26
通讯作者: 许林勇,男,博士,副教授,硕导,研究方向:临床研究数据管理和临床疗效与安全评价,医学统计方法及其应用。 E-mail: xybms@163.com
作者简介:倪平,女,在读硕士研究生,研究方向:卫生统计学。 Tel: 13875851460 E-mail: np981128@126.com
基金资助:
国家“重大新药创制”科技重大专项:重大疾病新药临床评价研究综合技术平台建设(2012ZX09303014-001; 湖南省自然科学利培酮治疗精神分裂症的个体化剂量预测模型研究(13JJ5017)

Assessing the agreement of quantitative data by Bland-Altman method and realizing it with SAS Macro

NI Ping¹, CHEN Hui¹, TU Jiao¹, XU Lin yong²

¹ Statistics Department,Public Health Academy,Central South University,Changsha 410078,Hunan,China;
² Clinical Drug Research and Statistical Analysis Center, the Third Xiangya Hospital,Central South University,Changsha 410013,Hunan,China

Received:2014-04-21 Revised:2014-07-18 Online:2014-08-26 Published:2014-08-26

摘要/Abstract

摘要： 目的探讨Bland-Altman在定量资料一致性评价方面的应用,并用SAS宏实现该过程。方法根据Bland-Altman法的相关原理及一致性分析的步骤,编写SAS宏命令。结果编写的SAS宏能够运用Bland-Altman法对定量资料的一致性进行分析,并能实现分析结果中图和表的word输出,可以为临床试验的统计分析节约时间。结论定量资料的一致性评价应该采用Bland-Altman法,SAS宏为该方法提供了很大的方便,有助于其推广应用。

关键词: 定量资料, 一致性评价, Bland-Altman, SAS宏

Abstract: AIM: To explore the application of Bland-Altman in quantitative data consistency evaluation,and realize it with SAS macro. METHODS: According to the principle of Bland-Altman method and the steps of the consistency analysis, we wrote SAS macro command.RESULTS: The SAS macro could use the Bland-Altman method to evaluate the consistency of quantitative data, and output graph and table results of analysis into word, save a lot of time for clinical trial statistics. CONCLUSION: Consistency evaluation of quantitative data should use the Bland-Altman method, the SAS macro provided great convenience for the method, contributed to its popularization and application.

Key words: quantitative data, agreement assessment, Bland-Altman, SAS Macro

中图分类号:

R969

倪平, 陈卉, 涂娇, 许林勇. 基于Bland-Altman法对定量资料的一致性评价及其SAS宏实现[J]. 中国临床药理学与治疗学, 2014, 19(8): 898-903.

NI Ping, CHEN Hui, TU Jiao, XU Lin yong. Assessing the agreement of quantitative data by Bland-Altman method and realizing it with SAS Macro[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(8): 898-903.

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