[1]Hoshii T,Tadokoro Y,Naka K,et al.mTORC1 is essential for leukemia propagation but not stem cell self-renewal[J].J Clin Invest,2012,122(6):2114-2129.
[2]Bobbala D, Kandhi R,Chen X, et al.Interleukin-15 deficiency promotes the development of T-cell acute lymphoblastic leukemia in non-obese diabetes mice with severe combined immune- deficiency[J]. Leukemia, 2016,30(8):1749-1752.
[3]Fortier JM, Graubert TA.Murine models of human acute myeloid leukemia[J]. Cancer Treat Res, 2010, 145(145):183-196.
[4]Marschalek R.Mechanisms of leukemogenesis by MLL fusion proteins[J].Br J Haematol,2011,152(2):141-154.
[5]Dick JE, Lapidot T. Biology of normal and acute myeloid leukemia stem cells[J].Int J Hematol,2005,82(5):389-396.
[6]Bonnet D.Normal and leukaemic stem cells [J].Br J Haematol,2005,130(4):469-479.
[7]Hope KJ, Jin L, Dick JE.Acute myeloid leukemia originates from a hierarchy of leukemic stem cell slasses that difer in self-renewal capacity [J].Nat Immunol,2004,5(7):738-743.
[8]Fortier JM, Graubert TA. Murine models of human acute myeloid leukemia[J]. Cancer Treat Res,2010,145:183-196.
[9]McCormack E, Bruserud O, Gjertsen BT.Animal models of acute myelogenous leukaemia-development, application and future perspectives[J]. Leukemia, 2005,19(5):687-706.
[10]Shultz LD,Ishikawa F,Greiner DL.Humanized mice in translational biomedical research[J].Nat Rev Immunol,2007,7(2):118-130.
[11]Shuhz LD,Brehm MA,Garcia-Martinez JV,et al.Humanized mice for immune system investigation:progress,promise and challenges[J].Nat Rev Immunol,2012,12(11):786-798.
[12]Agliano A,Martin-Padura I,Mancuso P,et al.Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains[J].Int J Cancer,2008,123(9):2222-2227.
[13]Brehm MA, Racki WJ, Leif J, et al.Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rgamma null mice is enhanced by transgenic expression of membrane-bound human SCF[J].Blood,2012,119(12):2778-2788.
[14]Ito R, Takahashi T, Katano I, et al.Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice[J]. J Immunol,2013,191(6):2890-2899.
[15]Meyer LH, Debatin KM.Diversity of human leukemia xenograft mouse models: implications for disease biology[J]. Cancer Res,2011,71(23):7141-7144.
[16]Reinisch A, Thomas D, Corces MR, et al.A humanized bone marrow ossicle xenotransplant- ation model enables improved engraftment of healthy and leukemic human hematopoietic cells[J].Nature Med, 2016, 22(7):812-821.
[17]Kong Y, Yoshida S, Saito Y, et al. CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL[J]. Leukemia, 2008, 22(6):1207-1213.
[18]Spiegel A, Kollet O, Peled A, et al. Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling[J].Blood,2004, 103(8):2900-2907.
[19]Willinger T, Rongvaux A, Strowig T, et al. Improving human hemato- lymphoid -system mice by cytokine knock-in gene replacement[J]. Trends Immunol, 2011, 32 (7):321-327.
[20]Aliperta R,Cartellieri M,Feldmann A,et al.Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts[J].Blood Cancer J,2015,5(9):e348.
[21]Wunderlich M,Chou FS, Link KA, et al. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3[J]. Leukemia, 2010, 24(10):1785-1788.
[22]Cosgun KN, Rahmig S, Mende N, et al.Kit regulates HSC engraftment across the human-mouse species barrier[J]. Cell Stem Cell,2014,15(2):227-238.
[23]McIntosh BE, Brown ME, Duffin BM, et al. Nonirradiated NOD,B6.SCID Il2rgamma-/- Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells[J]. Stem Cell Reports,2015,4(2):171-180.
[24]Rongvaux A, Willinger T, Takizawa H, et al.Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo[J]. Proc Natl Acad Sci USA,2011, 108(6):2378-2383.
[25]Mendelson A, Frenette PS.Hematopoietic stem cell niche maintenance during homeostasis and regeneration[J]. Nature Medicine, 2014, 20(8):833-846.
[26]Chalign R, Tonetti C, Besancenot R, et al. New mutations of MPL in primitive myelofibrosis: Only the MPL W515 mutations promote a G1/S-phase transition[J]. Leukemia,2008,22(8):1557-1566.
[27]Friedenstein AJ, Gorskaja JF, Kulagina NN.Fibroblast precursors in normal and irradiated mouse hematopoietic organs[J]. Exp Hematol,1976,4(5):267-274.
[28]Luria EA, Owen ME, Friedenstein AJ, et al. Bone formation in organ cultures of bone marrow[J]. Cell Tissue Res,1987,248(2):449-454.
[29]Chen Y, Jacamo R, Shi YX, et al.Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment[J]. Blood,2012, 119 (21) :4971-4980.
[30]Groen RW, Noort WA, Raymakers RA, et al.Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma[J].Blood,2012,120(3):e9-e16.
[31] Doulatov S, Notta F, Laurenti E, et al. Hematopoiesis: A Human Perspective[J]. Cell Stem Cell, 2012, 10(2):120-136.
[32]Manz MG. Human-hemato-lymphoid-system mice: opportunities and challenges [J]. Immunity, 2007, 26(5):537-541.
[33]Rongvaux A, Takizawa H, Strowig T, et al. Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine[J]. Immunol, 2013, 31(31):635-674.
[34]Li L,Bhatia R.Stem cell quiescence[J].Clin Cancer Res,2011,17 (15):4936-4941.
[35]Brehm MA, Cuthbert A, Yang C, et al. Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.[J]. Clin Immunol, 2010, 135(1):84-98.
[36]Covassin L, Jangalwe S, Jouvet N, et al. Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells[J]. Clin Exp Immunol, 2013, 174(3):372-388.
[37]McCune JM, Namikawa R, Kaneshima H, et al. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function[J].Science,1988,241(4873): 1632-1639.
[38]Greenblatt MB, Vrbanac V, Tivey T, et al. Graft versus host disease in the bone marrow, liver and thymus humanized mouse model [J]. Plos One, 2013, 8(5):e44664.
[39]Lapidot T, Pflumio F, Doedens M, et al.Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice [J]. Science,1992,255(5048):1137-1141.
[40]Deng K, Pertea M, Rongvaux A, et al. Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations[J].Nature,2015,517(7534):381-385.
[41]Yoshihara H, Arai F, Hosokawa K, et al. Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche [J]. Cell Stem Cell, 2007, 1(6):685-697.
[42]Satoh Y, Matsumura I, Tanaka H, et al.C-terminal mutation of RUNX1 attenuates the DNA-damage repair response in hematopoietic stem cells[J]. Leukemia, 2011, 26(2):303-311.
[43]Schr?der JK, Kolkenbrock S, Tins J, et al. Analysis of thrombopoietin receptor (c-mpl) mRNA expression in de novo acute myeloid leukemia[J]. Leuk Res, 2000, 24(5):401-409.
[44]Rongvaux A, Willinger T, Martinek J, et al.Development and function of human innate immune cells in a humanized mouse model[J].Nat Biotechnol,2014,32(4):364-372.
[45]Lee MW, Kim HJ, Yoo KH, et al. Establishment of a bioluminescent imaging-based in vivo leukemia model, by intra-bone marrow injection[J].Int J Oncol, 2012, 41(6):2047-2056.
[46]Nwajei F, Konopleva M.The Bone marrow microenvironment as niche retreats for hematopoietic and leukemic stem cells[J]. Adv Hematol, 2013, 2013(8): 953982.
[47]Kremer KN,Dudakovic A,Mcgeelawrence ME,et al.Osteoblasts protect AML cells from SDF-1-induced apoptosis[J].J Cell Biochem,2014,115(6):1128-1137.
[48]Asiedu KO, Koyasu S, Szajek LP, et al. Bone marrow cell trafficking analyzed by 89Zr-oxine positron emission tomography in a murine transplantation model[J]. Clin Cancer Res,2017,23(11):2759-2768. |