烟、酒致骨质疏松症的实验研究进展

中国临床药理学与治疗学 ›› 2017, Vol. 22 ›› Issue (11): 1299-1303.

烟、酒致骨质疏松症的实验研究进展

李晓莉¹，沙南南²，陈楠²，王拥军²，张岩²

¹上海理工大学医疗器械与食品学院, 上海 200093；²上海中医药大学附属龙华医院，上海200032

收稿日期:2017-05-24 修回日期:2017-06-12 出版日期:2017-11-26 发布日期:2017-12-11
通讯作者: 张岩，男，博士，研究员/教授，博士生导师，研究方向：药理学。 Tel:021-64385700 E-mail:medicineyan@aliyun.com
作者简介:李晓莉，女，博士，研究方向：中药药理学。 Tel:021-55271200 E-mail:xli@usst.edu.cn
基金资助:
国家中医临床研究基地龙医创新团队资助（LYCX-01）；上海市自然科学基金（17ZR1430800）

Experimental study progress of smoking- and alcohol-induced osteoporosis

LI Xiaoli¹, SHA Nannan ², CHEN Nan ², WANG Yongjun², ZHANG Yan²

¹ School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; ²Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China

Received:2017-05-24 Revised:2017-06-12 Online:2017-11-26 Published:2017-12-11

摘要/Abstract

摘要：

生活方式与骨质疏松症的发生密切相关。吸烟、酗酒都是骨质疏松症发病的高风险因素。本文分别从生物模型、动物实验、细胞实验、分子机制等方面综述吸烟性骨质疏松症、酒精性骨质疏松症的最新研究进展。

关键词: 吸烟, 酒精, 骨质疏松

Abstract:

Life style closely correlates with the occurrence of osteoporosis. Both smoking and drinking are high risk factors for osteoporosis. This review summarized the updated research progress on biological models, animal and cell experiments, and molecular mechanisms for smoking- and alcohol-induced osteoporosis.

Key words: smoking, alcohol, osteoporosis

中图分类号:

R681

李晓莉，沙南南，陈楠，王拥军，张岩. 烟、酒致骨质疏松症的实验研究进展[J]. 中国临床药理学与治疗学, 2017, 22(11): 1299-1303.

LI Xiaoli, SHA Nannan, CHEN Nan, WANG Yongjun, ZHANG Yan. Experimental study progress of smoking- and alcohol-induced osteoporosis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2017, 22(11): 1299-1303.

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