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中国临床药理学与治疗学 ›› 2026, Vol. 31 ›› Issue (2): 162-167.doi: 10.12092/j.issn.1009-2501.2026.02.003

• “癫痫药物治疗研究进展”专栏 • 上一篇    下一篇

女性癫痫患者的临床特点和药物治疗研究进展

赵正卿(), 李雁鹏, 赵忠新()   

  1. 海军军医大学长征医院神经内科,上海 200003
  • 收稿日期:2025-05-27 修回日期:2025-09-15 出版日期:2026-02-26 发布日期:2026-03-17
  • 通讯作者: 赵忠新 E-mail:zhaozhengqing83@hotmail.com;neuzhaozx@163.com
  • 作者简介:赵正卿,女,博士, 副主任医师,研究方向:睡眠障碍、癫痫、肌张力障碍。E-mail:zhaozhengqing83@hotmail.com
  • 基金资助:
    国家自然科学基金(81671314);中国老年保健协会课题(KT202508001)

Clinical characteristics and medicine treatment progress in female patients with epilepsy

Zhengqing ZHAO(), Yanpeng LI, Zhongxin ZHAO()   

  1. Department of Neurology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China
  • Received:2025-05-27 Revised:2025-09-15 Online:2026-02-26 Published:2026-03-17
  • Contact: Zhongxin ZHAO E-mail:zhaozhengqing83@hotmail.com;neuzhaozx@163.com

摘要:

女性癫痫患者相对男性癫痫患者而言,受激素水平变化、生理周期、生育需求等因素影响,其临床特点具有一定的特殊性,在选择抗癫痫发作药物时需兼顾疗效和安全性,存在一定的挑战性。本文重点分析了处于不同生理时期的女性癫痫患者的不同临床特点,并就女性癫痫患者在不同时期的药物治疗选择以及治疗的新进展进行综述和展望。

关键词: 女性癫痫, 妊娠, 抗癫痫发作药物, 激素

Abstract:

Compared with male epilepsy patients, female epilepsy patients have certain clinical characteristics due to factors such as hormone level changes, menstrual cycles, and fertility needs, and the selection of treatment drugs needs to take into account both efficacy and safety, which has certain challenges. This article focuses on the clinical characteristics of female epilepsy patients, especially on the analysis of the different clinical characteristics at different physiological periods. This paper also reviews and prospects the medical treatment options at different periods and new advances in treatment for female patients with epilepsy.

Key words: female epilepsy, pregnancy, anti-seizure medications, hormones

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