木瓜三萜联合美沙拉嗪对溃疡性结肠炎临床疗效、炎症因子及肠黏膜屏障保护因子的影响

doi:10.12092/j.issn.1009-2501.2018.10.013

中国临床药理学与治疗学 ›› 2018, Vol. 23 ›› Issue (10): 1165-1173.doi: 10.12092/j.issn.1009-2501.2018.10.013

木瓜三萜联合美沙拉嗪对溃疡性结肠炎临床疗效、炎症因子及肠黏膜屏障保护因子的影响

张继红¹, 李小妹², 石孟琼³, 熊兴军⁴, 李小琴², 冯旻璐², 许海燕², 杨文雁³, 覃慧林¹, 罗涛¹

¹三峡大学中医医院&宜昌市中医医院消化内科, 宜昌 443001, 湖北； ²三峡大学生物与制药学院天然产物研究与利用湖北省重点实验室, 宜昌 443002, 湖北；³三峡大学医学院基础医学实验中心, 宜昌 443002, 湖北； ⁴长阳县中医医院药剂科, 长阳 443501, 湖北

收稿日期:2018-05-14 修回日期:2018-06-22 出版日期:2018-10-26 发布日期:2018-10-25

Effects of Muguasantie combined with mesalazine on the clinical efficacy, inflammatory and intestinal barrier protective factors of ulcerative colitis

ZHANG Jihong¹, LI Xiaomei², SHI Mengiong³, XIONG Xiinjun⁴, LI Xiaoqin², FENG Minlu², XU Haiyan², YANG Wenyan³, QIN Huilin¹, LUO Tao¹

¹Department of Gastroenterology, Traditional Chinese Medicine Hospital of China Three Gorges University & Yichang Hospital of Traditional Chinese Medicine, Yichang 443001, Hubei, China; ²Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, Hubei, China; ³Experimental Center of Basic Medicine, College of Medical Sciences, China Three Gorges Universtiy, Yichang 443002, Hubei, China; ⁴ Pharamacy Department, Changyang Hospital of Traditional Chinese Medicine, Changyang 443501, Hubei, China

Received:2018-05-14 Revised:2018-06-22 Online:2018-10-26 Published:2018-10-25

摘要/Abstract

张继红, 李小妹, 石孟琼, 熊兴军, 李小琴, 冯旻璐, 许海燕, 杨文雁, 覃慧林, 罗涛. 木瓜三萜联合美沙拉嗪对溃疡性结肠炎临床疗效、炎症因子及肠黏膜屏障保护因子的影响[J]. 中国临床药理学与治疗学, 2018, 23(10): 1165-1173.

ZHANG Jihong, LI Xiaomei, SHI Mengiong, XIONG Xiinjun, LI Xiaoqin, FENG Minlu, XU Haiyan, YANG Wenyan, QIN Huilin, LUO Tao. Effects of Muguasantie combined with mesalazine on the clinical efficacy, inflammatory and intestinal barrier protective factors of ulcerative colitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2018, 23(10): 1165-1173.

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木瓜三萜联合美沙拉嗪对溃疡性结肠炎临床疗效、炎症因子及肠黏膜屏障保护因子的影响

Effects of Muguasantie combined with mesalazine on the clinical efficacy, inflammatory and intestinal barrier protective factors of ulcerative colitis

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