葛根素药理作用机制探讨及临床应用

摘要/Abstract

摘要： 葛根素是葛根的重要有效活性成分。其药理作用复杂,药效活性强。葛根素已经开发为葛根素注射剂,应用于心脑血管疾病如心律失常、心肌缺血、高血压等的治疗。本文对葛根素的药理作用机制及临床应用研究进展进行综述。

Abstract: As a saft and effective traditional Chinese medicine’s parenteral in jection, puerarin, whose molecular formula is 4,7-dihydroxy- 8β-D glucose isoflavone, has comprehensive and extensive phammaco logical action, and is generally used for treatment of cardiovascu lar and cerebrov ascular system diseases such as arhythmia, myocardial ischemia and hypertension.It has an extensive deve lopment perspective. The recent research in the mechanism of phamacological action and clinical application W ere review ed.

Key words: puerarn, pharmaoologic action, clinical application

中图分类号:

R965

姚丹, 丁选胜. 葛根素药理作用机制探讨及临床应用[J]. 中国临床药理学与治疗学, 2008, 13(4): 468-474.

YAO Dan, DING Xuan-sheng. Discussions in pharmacological action and the development in clinical application of puer arin[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(4): 468-474.

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