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中国临床药理学与治疗学 ›› 2022, Vol. 27 ›› Issue (4): 428-432.doi: 10.12092/j.issn.1009-2501.2022.04.012

• 心血管疾病药物治疗最新研究进展 • 上一篇    下一篇

高血压合并高尿酸血症的应对之策

李远方,崔兆强
  

  1. 复旦大学附属中山医院心内科,上海市心血管病研究所,上海 200032
  • 出版日期:2022-04-26 发布日期:2022-05-17
  • 通讯作者: 崔兆强,男,博士,教授,博士生导师,研究方向:高血压病发病机制与临床治疗。 E-mail: zhaoq_cui@163.com
  • 作者简介:李远方,女,医学博士,主治医师,研究方向:难治性高血压,靶向治疗相关高血压。 E-mail: li.yuanfang@zs-hospital.sh.cn

Treatment of hypertension complicated with hyperuricemia

LI Yuanfang, CUI Zhaoqiang   

  1. Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai 200032, China
  • Online:2022-04-26 Published:2022-05-17

摘要: 高血压和高尿酸血症发病率高、危害大,且二者常合并存在,值得临床人员重视。目前的共识及指南推荐积极控制尿酸和血压水平,但是对于高血压与高尿酸合并存在的患者,如何规范治疗方案,避免药物对合并症的不良影响,目前的指南和共识有原则性的推荐,但缺乏细则。本文对高血压合并高尿酸血症的流行病学及临床危害、高血压合并无症状高尿酸血症的治疗目标值、治疗措施中的共识和争议等进行了文献复习,综述如下。

关键词: 高血压, 高尿酸血症, 噻嗪类利尿剂, 血管转化酶受体抑制剂, 黄嘌呤氧化酶抑制剂

Abstract: Hypertension and hyperuricemia often coexist, and have a high incidence and often incur great harm. The current guidelines recommend active control of uric acid and blood pressure levels. But patients with high uric acid and high blood pressure still need detailed guidelines to standardize the treatment to avoid incurring more drug-related side effects. This article reviews the epidemiology and clinical harm, the therapeutic target value, the consensus and controversy on therapeutic treatment of high blood pressure combined with high uric acid.

Key words: hypertension, hyperuricemia, thiazide diuretics, angiotonin receptor blocker, xanthine oxidase inhibitor

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