赵忠新,《中国临床药理学与治疗学》杂志副主编,海军军医大学上海长征医院神经内科主任医师,教授,博士生导师,主要从事神经病学临床研究:癫痫,脑血管病,睡眠障碍,E-mail:zhaozxn@126.com。 教育经历:1990-1993,第二军医大学神经病学,硕士研究生;1978-1983,第二军医大学医疗系,本科。 荣誉及学术任职:中国医师协会神经内科分会常委;中国医师协会睡眠医学专业委员会副主任委员;中国睡眠研究会副理事长;上海医学会理事;2017年中国医师协会授予“中国杰出睡眠医师”;2018年荣获第二届“国家名医·卓越建树”称号;“十三五”全国高等学校教材《睡眠医学》主编。 承担的研究课题: 1.国家自然科学基金(2012-2015):项目编号:81171252。项目名称:WNK3激酶调控SCN区昼夜节律的机制研究; 2.国家自然科学基金(2011-2014)(30900473):项目批准号:81070070。项目名称:GH/IGF-1轴在睡眠片段现象导致认知功能损害中的作用及机制 3.国家自然科学基金(2002-2013)项目批准号30270487: 睡眠剥夺对脑神经元的损伤和能量代谢的影响; 4.国家科学技术学术著作出版基金(2002): 《临床睡眠障碍学》 5.国家科技重大专项课题(科技部)(重大新药创制)睡眠控制新药临床评价技术平台构建(2011.1-2015.12)课题编号:2011ZXJ09202-015; 6.上海科委重点项目(2011-2013),(课题编号11411950203):慢性失眠规范化诊断与治疗方案的多中心临床研究 7.上海市科委重大项目“老年性痴呆的早期预防与诊治研究”分课题(课题编号09DZ1950400),老年性痴呆的睡眠特征与脑脊液生物标记的相关性及其早期诊断价值的研究; 8.上海市科技发展基金(项目批准号08411950800),血管性认知障碍非痴呆型临床与实验研究; 9.上海市科技发展基金(项目批准号08411950700),睡眠与Alzheimer病关系的研究; 10.全军医学科学技术研究“十一五”计划保健专项课题(项目批准号07BJZ06),中老年慢性失眠规范化诊断与治疗方案的临床研究(2007); 11.上海市重大项目研究基金(项目批准号03DZ19703),脑卒中的二级预防研究(2003); 12.上海市科技发展基金(项目批准号024119029),睡眠剥夺对认知功能的影响及其可能机制的研究 (2002); 代表性论文: 1. Xiangxiang Zhao, Yanpeng Li, Qing Tian, Bingqian Zhu, Zhongxin Zhao. Repetitive transcranial magnetic stimulation increases serum brain-derived neurotrophic factor and decreases interleukin-1β and tumor necrosis factor-α in elderly patients with refractory depression .Journal of International Medical Research, First Published 7 Jan 2019(https://journals.sagepub.com/doi/10.1177/0300060518817417) 2. Hongyi Zhao, Huijuan Wu, Jialin He, Jianhua Zhuang, Zhenyu Liu, Yang Yang, Liuqing Huang, Zhongxin Zhao, Frontal cortical mitochondrial dysfunction and mitochondria-related β-amyloid accumulation by chronic sleep restriction in mice, NeuroReport, 2016, 27(12), 916-922. 3. Hong-Yi Zhao, Hui-Juan Wu, Jia-Lin He, Jian-Hua Zhuang, Zhen-Yu Liu, Liu-Qing Huang, Zhong-Xin Zhao, Chronic Sleep Restriction Induces Cognitive Deficits and Cortical Beta-Amyloid Deposition in Mice via BACE1-Antisense Activation, CNS Neuroscience & Therapeutics, 2017, 23, 3 4. Xing Xu, Huijuan Wu, Jianhua Zhuang, Kun Chen, Bei Huang, Zhengqing Zhao, Zhongxin Zhao, Sleep-wake patterns,non ?rapid eye movement, and rapid eye movement sleep cycles in teenage narcolepsy, Sleep Medicine, 2016, DOI: http://dx.doi.org/10.1016/j.sleep.2016.08.012. 5. Cheng Chu, Zhongxin Zhao. Article: MicroRNA in the molecular mechanism of the circadian clock in mammals .Frontiers in Bioscience 01/2013; 18(2).441-446. DOI: 10.2741/4112 ? 6. Zongwen Wang, Huijuan Wu, William S. Stone, Jianhua Zhuang, Linli Qiu, Xing Xu, Yan Wang, Zhengqing Zhao, Fang Han,Zhongxin Zhao, Body weight and basal metabolic rate in childhood narcolepsy: a longitudinal study, Sleep Medicine, 2016, 25,139-144 7. Wang Y, Yang Y, Wu H, Lan D, Chen Y, Zhao Z. Effects of rotigotine on REM sleep behavior disorder in Parkinson disease. J Clin Sleep Med 2016;12(10):1403–1409. http://dx.doi.org/10.5664/jcsm.6200 8. Yin, You; Liu, Yan; Zhuang, Jianhua; Pan, Xiao; Li, Peng; Yang, Yuechang; Li, Yan-Peng; Zhao, Zheng-Qing; Huang, Liu-Qing; *Zhao, Zhong-Xin.Low-Dose Atypical Antipsychotic Risperidone Improves the 5-Year Outcome in Alzheimer's Disease Patients with Sleep Disturbances . Pharmacology, 2015,96(3-4): 155-162. 9. Yin Y, Liu Y, Pan X, Chen R, Li P, Wu HJ, Zhao ZQ, Li YP, Huang LQ, Zhuang JH1, Zhao ZX. Interleukin-1β Promoter Polymorphism Enhances the Risk of Sleep Disturbance in Alzheimer's Disease. PLoS One. 2016,11(3):DOI:10.1371/journal.pone.0149945. 10.Lan, Danmei; Wang, Wenzhao; Zhuang, Jianhua; *Zhao, Zhongxin. Proteasome inhibitor-induced autophagy in PC12 cells overexpressing A53T mutant α-synuclein. Molecular Medicine Reports, .2015;11(3):1655-1660.This study was supported by grants from the Natural Science Foundation of China (nos. 30600663 and 81070070) and the Ministry of Science and Technology Plan Fund Major Projects (no. 2011ZXJ09202 015) 11.Huijuan Wua, b, Jianhua Zhuanga, 1, William S. Stonec, Lin Zhanga, Zhengqing Zhaoa, Zongwen Wanga, Yang Yanga, Xiang Lia, Xiangxiang Zhaoa, b, Zhongxin Zhaoa, b,,Symptoms and occurrences of narcolepsy: a retrospective study of 162 patients during a10-year period in Eastern China. Sleep Medicine. 2014, 15(6):607–613. 12.Zhao, Zhengqing; Li, Yanpeng; Chen, Haiyan; Huang, Liuqing; Zhao, Fei; Yu, Qiang; Xiang, Zhenghua; *Zhao, Zhongxin.Xylaria nigripes mitigates spatial memory impairment induced by rapid eye movement sleep deprivation. International journal of clinical and experimental medicine .2014; 7(2):356-362 13.Zhengqing Zhao, Yanpeng Li, Zhongxin Zhao.Xylaria nigripes wuling mitigates spatial memory impairment induced by rapid eye movement sleep deprivation in the rat.Sleep Medicine.2011;12(Suppl .1):S41-42. 14.Chu, Cheng; *Zhao, Zhongxin, MicroRNA in the molecular mechanism of the circadian clock in mammals, Frontiers in Bioscience, 2013,18: 441-446 15.Chen Xu, Li Qiang, Cao Limei, Zhang Yan, Zheng Jia, Dong Zhiqiang, Zhongxin Zhao. Correlation Between Cerebral Infarction and ALOX5AP Gene Expression. Cell Biochemistry and Biophysics..2013;67:899-904.