关键词: 注意缺陷多动障碍, 哮喘, 过敏性疾病, 儿童

Abstract: Objective To explore the association between attention deficit hyperactivity disorder (ADHD) and asthma and allergic disease in children. Methods A 1∶1 matched case-control study of 278 children with ADHD and 278 normal children were investigated in asthma and allergic disease.The Chi-square test was used to test single factors while multi-factors inspection was test by conditional Logistic regression analysis. Results The suffering from asthma and eczema in cases and control group had no significant difference (2.9% vs 1.1%, 4.3% vs 1.8%, respectively, P>0.05).The incidence of allergic phenomenon such as itchy rash for six months, once diagnosed rhinitis, recent one year to have asthma symptom, and often have a runny nose, itchy eyes, nasal congestion were significantly higher than those of control group (P<0.05).Allergic rhinitis (P=0.029, OR=2.021, 95%CI:1.074~3.803), and often have a runny nose, eye itching, nasal congestion (P=0.012, OR=1.863, 95%CI:1.147~3.024) were risk factors for ADHD by conditional Logistic regression analysis. Conclusions Allergic rhinitis with a runny nose, itchy eyes, nasal congestion are associated with ADHD.Further studies need to be done in exploring the relationship of asthma or eczema with ADHD.

Key words: attention deficit hyperactivity disorder, asthma, allergic rhinitis, children