关键词: 双酚A, 肥胖, 儿童

Abstract: Objective To explore status quo of Shanghai school-age children exposed to bisphenol A (BPA) and the relationship between BPA exposure with children obesity. Method A total of 500 primary school students aged between 6 and 11 were collected,used high performance liquid chromatography (HPLC) method to detect the concentration of total BPA,measured and evaluated their physique level. Results Urine BPA detection rate of children detected was 77.2%,the concentration range was ND ~ 79.52 ng/mL,the median was 1.32 ng/mL,the interquartile range was 0.35~4.01 ng/mL.The urine BPA concentration was significantly higher in girls than boys (Z=-3.687,P<0.01);The urine BPA concentration was significantly higher in 8~11 age group than 6~7 age group (Z=-1.986,P<0.05).The obesity and overweight rate was as high as 32.9%,including the obesity rate-12.9%,the overweight rate-20.1%;and the angular rate was 2.6%.The obesity rate was significantly higher in boys than in girls(χ²=24.935,P<0.01).There was no significant difference between urine BPA concentrations of obese,overweight,angular and normal weight groups (P>0.05). Conclusion Shanghai school-age children are exposed to BPA generally.Severe obesity problem exists among school-age children.

Key words: bisphenol A, obesity, children