关键词: 听力筛查, 耳声发射, 自动听性脑电反应, 灵敏度, 特异度

Abstract: Objective To learn the sensitivity,specificity,the rate of missed diagnosis,misdiagnosis rates of otoacoustic emission (OAE),auto auditory brainstem respons (AABR) and the combined screening. Method OAE hearing screening were carried out in the 3~5 d after birth,each referred infant received OAE joint AABR screening in 42 days after birth.Those who have not passed the combined screening referral to higher hospital for ABR,acoustic impedance examination and the diagnosis and classification of hearing impairment.AABR and OAE as a parallel method of testing,anyone of the two method referred was positive,both of them passed was negative. Results 1 271 newborns received OAE and AABR combined screening,1 064 passed,207 did not pass.The sensitivity of OAE screening in the 42 days after birth was slightly higher;Compared with OAE,AABR screening had a lower sensitivity and higher specificity;Combined screening had improved the sensitivity and reduced the rate of missed diagnosis than a single method of screening. Conclusion Using OAE newborn hearing screening have a higher rate of missed diagnosis,OAE and AABR combined screening can effectively reduce the rate of missed diagnosis,and therefore worthy to be popularized.

Key words: hearing screening, otoacoustic emission, auto auditory brainstem respons, sensitivity, specificity