关键词: 维生素A, 性别, 感染, 住院新生儿

Abstract: Objective To evaluate the level of plasma vitamin A(VA) and the influencing factors of VA level in 212 hospitalized newborns. Methods The plasma level of VA in newborns was tested by high performance liquid chromatography(HPLC) from June to December 2017.And the general data of children were collected.SPSS 19.0 were used to analyze the influencing factors of VA level. Results There were 189(89.1%) cases were detected with VA deficiency. Gender,age,blood glucose,infection and neonatal respiratory distress syndrome(NRDS) were factors influencing VA concentration,and the difference was statistically significant(P<0.05). The level of VA was negatively correlated with C-reaction protein(CRP)(r=-0.167,P=0.015). The correlation between mother and neonates was not statistically significant(P＞0.05).Gender(OR=0.465,95%CI:0.237-0.913,P=0.026) and infection(OR=2.583,95%CI:1.135-5.876,P=0.024) were the risk factors for clinical VA deficiency. Conclusion Vitamin A deficiency in newborns is severe. Male infants and newborns with infection are prone to developing clinical vitamin A deficiency.

Key words: vitamin A, sex, infection, hospitalized newborns