关键词: 睑板腺囊肿, 维生素, 饮食习惯, 病因学, 儿童

Abstract: Objective Toinvestigate the etiology of chalazia in children,in order to provide basis for clinical prevention and treatment of chalazia. Methods Totally 108 preoperative children with chalazia were randomly selected as the case group from 2016 to 2017 in Children's Hospital of Fudan University,and 48 preoperative children with strabismus or trichiasis were as the control group. Serum vitamin A,B1,C,D,E of children were tested and compared in two groups using two independent samples t test. Questionnaires survey was conducted to investigate high-calorie food,snacks and meat consumption and dietary bias in two groups. Chi-square test and Logistic regression were used to analyze the data. Results The average serum vitamin A level of the case group was (0.64±0.14)μmol/L,the control group was (0.70±0.21 )μmol/L,and the difference between the two groups was statistically significant(P=0.014). Serum vitamin A levels in children with multiple cysts were lower than those of children with single cyst(P=0.006). There were no significant differences on serum vitamin B1,C,D and E levels between the two groups(P>0.05). But there were no significant differences on high-calorie food,snacks and meat consumption and dietary bias between case group and control group(P>0.05). Logistic regression analysis showed significant effect of eating habits to chalazia in children was not found(P>0.05). Conclusion Low vitamin A level is associated with chalazia in children,especially in children with multiple cysts.

Key words: chalazia, vitamin, eating habits, etiology, children