胎儿宫内发育迟缓的危险因素及孕期运动对其干预作用的研究进展

doi:10.11852/zgetbjzz2021-1499

中国儿童保健杂志 ›› 2022, Vol. 30 ›› Issue (10): 1091-1094.DOI: 10.11852/zgetbjzz2021-1499

胎儿宫内发育迟缓的危险因素及孕期运动对其干预作用的研究进展

郭长胜¹, 乌云塔娜¹, 王艳², 代剑洋¹, 杨楠¹, 裴飞²

1.黑龙江中医药大学,黑龙江哈尔滨 150040;
2.黑龙江中医药大学附属第二医院康复中心

收稿日期:2021-10-04 修回日期:2021-12-14 发布日期:2022-10-14 出版日期:2022-10-10
通讯作者: 王艳,E-mail:swallow-1113@163.com
作者简介:郭长胜(1998-),男,黑龙江人,硕士研究生在读,主要研究方向为儿童康复。
基金资助:
黑龙江中医药大学“优秀创新人才支持计划”科研项目(2018RCL10)

Research progress in the risk factors of fetal intrauterine growth retardation and the intervention effect of exercise during pregnancy

GUO Chang-sheng^*, WU Yun-ta na, WANG Yan, DAI Jian-yang, YANG Nan, PEI Fei

^*Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China

Received:2021-10-04 Revised:2021-12-14 Online:2022-10-10 Published:2022-10-14
Contact: WANG Yan, E-mail:swallow-1113@163.com

摘要/Abstract

摘要： 良好的宫内环境与胎儿健康及发育关系密切,但多种危险因素可以导致宫内发育迟缓的发生。运动作为一种有效的干预方式被广泛的应用于孕期,合理的运动更是可以预防胎儿的不良结局并促进胎儿的发育。本文将从宫内发育迟缓的危险因素以及孕期运动的干预作用两方面进行综述,以期为后续研究提供借鉴。

关键词: 孕期运动, 宫内发育迟缓, 母体, 胎儿

Abstract: A good intrauterine environment is closely related to fetal health and development, but a variety of risk factors can lead to intrauterine growth retardation. As an effective intervention, exercise is widely used in pregnancy. Appropriate exercise can prevent the adverse outcome of the fetus and promote the development of the fetus. The risk factors of intrauterine growth retardation and the intervention effect of exercise during pregnancy are summarized in this review, so as to provide reference for further researches.

Key words: exercise during pregnancy, intrauterine growth retardation, matrix, fetus

中图分类号:

R714.5

郭长胜, 乌云塔娜, 王艳, 代剑洋, 杨楠, 裴飞. 胎儿宫内发育迟缓的危险因素及孕期运动对其干预作用的研究进展[J]. 中国儿童保健杂志, 2022, 30(10): 1091-1094.

GUO Chang-sheng, WU Yun-ta na, WANG Yan, DAI Jian-yang, YANG Nan, PEI Fei. Research progress in the risk factors of fetal intrauterine growth retardation and the intervention effect of exercise during pregnancy[J]. Chinese Journal of Child Health Care, 2022, 30(10): 1091-1094.

参考文献

[1] Sharma D, Shastri S, Sharma P. Intrauterine growth restriction: Antenatal and postnatal aspects[J]. Clin Med Insights Pediatr,2016,10:67-83.
[2] Babbar S, Shyken J. Yoga in pregnancy[J].Clin Obstet Gynecol,2016,59(3):600-612.
[3] Bischoff AR, Cunha F, Dalle MR, et al. Is willingness to exercise programmed in utero? Reviewing sedentary behavior and the benefits of physical activity in intrauterine growth restricted individuals[J]. J Pediatr(Rio J),2018,94(6):582-595.
[4] Armengaud JB, Yzydorczyk C, Siddeek B, et al. Intrauterine growth restriction: Clinical consequences on health and disease at adulthood[J]. Reprod Toxicol,2021,99:168-176.
[5] Eremkina AK, Mokrysheva NG, Pigarova EA, et al. Vitamin D: effects on pregnancy, maternal, fetal and postnatal outcomes[J]. Ter Arkh,2018,90(10):115-127.
[6] Esposito ER, Horn KH, Greene RM, et al. An animal model of cigarette smoke-induced in utero growth retardation[J]. Toxicology,2008,246(2-3):193-202.
[7] Sharma D, Shastri S, Farahbakhsh N, et al. Intrauterine growth restriction-part 1[J]. J Matern Fetal Neonatal Med,2016,29(24):3977-3987.
[8] Banjac L, Kotur-Stevuljevic J, Gojkovic T, et al. Relationship between insulin-like growth factor type 1 and intrauterine growth[J]. Acta clin Croat,2020,59(1):91-96.
[9] Karimi-Zarchi M, Zanbagh L, Javaheri A, et al. Association of insulin-like growth factor-II Apa1 and MspI polymorphisms with intrauterine growth restriction risk[J]. Fetal Pediatr Pathol,2020,40(3):1-7.
[10] Sharma D, Farahbakhsh N, Shastri S, et al. Intrauterine growth restriction - part 2[J]. J Matern Fetal Neonatal Med,2016,29(24):4037-4048.
[11] Auriti C, De Rose DU, Santisi A, et al. Pregnancy and viral infections: Mechanisms of fetal damage, diagnosis and prevention of neonatal adverse outcomes from cytomegalovirus to SARS-CoV-2 and Zika virus[J]. Biochim Biophys Acta Mol Basis Dis,2021,1867(10):166198.
[12] Jahanfar S, Ho JJ, Jaafar SH, et al. Ultrasound for diagnosis of birth weight discordance in twin pregnancies[J]. Cochrane Database Syst Rev,2021,3(3).doi: 10.1002/14651858.CD012553.pub2.
[13] Heinonen S, Taipale P, Saarikoski S. Weights of placentae from small-for-gestational age infants revisited[J]. Placenta,2001,22(5):399-404.
[14] Salavati N, Smies M, Ganzevoort W, et al. The possible role of placental morphometry in the detection of fetal growth restriction[J]. Front Physiol,2019. doi:10.3389/fphys.2018.01884.
[15] Zygmunt M, Herr F, Münstedt K, et al. Angiogenesis and vasculogenesis in pregnancy[J]. Eur J Obstet Gynecol Reprod Biol,2003,110(Suppl):10-18.
[16] Djakovic A, Rieger L, Wirbelauer J, et al. Severe foetal growth retardation in a patient with uterus bicornis, velamentous insertion and partial placental abruption in the 26th week of gestation-a case report[J]. Z Geburtshilfe Neonatol,2007,211(4):169-173.
[17] Szentpéteri I, Rab A, Kornya L, et al. Placental gene expression patterns of endoglin(CD105) in intrauterine growth restriction[J]. J Matern Fetal Neonatal Med,2013,27(4):350-354.
[18] Traylor CS, Johnson JD, Kimmel MC, et al. Effects of psychological stress on adverse pregnancy outcomes and nonpharmacologic approaches for reduction:An expert review[J]. Am J Obstet Gynecol MFM,2020,2(4):100229.
[19] Bhattacharjee J, Mohammad S, Adamo KB. Does exercise during pregnancy impact organs or structures of the maternal-fetal interface?[J]. Tissue Cell,2021,72:101543.
[20] Nagpal TS, Bhattacharjee J, Da Silva DF, et al. Physical activity may be an adjuvant treatment option for substance use disorders during pregnancy: A scoping review[J]. Birth Defects Res,2021,113(3):265-275.
[21] Cooper DB,Yang L.Pregnancy and exercise[EB/OL].[2021-04-26]. https://pubmed2.ilibs.cn/books/NBK430821
[22] Gatford KL, Kaur G, Falcão-Tebas F, et al. Exercise as an intervention to improve metabolic outcomes after intrauterine growth restriction[J]. Am J Physiol Endocrinol Metab,2014,306(9):E999-E1012.
[23] Allehdan SS, Basha AS, Asali FF, et al. Dietary and exercise interventions and glycemic control and maternal and newborn outcomes in women diagnosed with gestational diabetes: Systematic review[J].Diabetes Metab Syndr,2019,13(4):2775-2784.
[24] Clapp JF. The effects of maternal exercise on fetal oxygenation and feto-placental growth[J]. Eur J Obstet Gynecol Reprod Biol,2003,110(Suppl):80-85.
[25] Davenport MH, Ruchat S, Poitras VJ, et al. Prenatal exercise for the prevention of gestational diabetes mellitus and hypertensive disorders of pregnancy:A systematic review and meta-analysis[J]. Br J Sports Med,2018,52(21):1367-1375.
[26] Cavalcante SR,Cecatti JG,Pereira RI,et al.Water aerobics Ⅱ:Maternal body composition and perinatal outcomes after a program for low risk pregnant women[J].Reprol Health,2009,6:1.
[27] Sechrist DM, Tiongco CG, Whisner SM, et al. Physiological effects of aquatic exercise in pregnant women on bed rest[J]. Occup Ther Health Care,2015,29(3):330-339.
[28] Clapp JF, Kim H, Burciu B, et al. Beginning regular exercise in early pregnancy: Effect on fetoplacental growth[J]. Am J Obstet Gynecol,2000,183(6):1484-1488.
[29] Son JS, Liu X, Tian Q, et al. Exercise prevents the adverse effects of maternal obesity on placental vascularization and fetal growth[J]. J Physiol,2019,597(13):3333-3347.
[30] Reyes LM, Davenport MH. Exercise as a therapeutic intervention to optimize fetal weight[J]. Pharmacol Res,2018,132:160-167.
[31] Hutchinson KA, Vuong NH, Mohammad S, et al. Physical activity during pregnancy is associated with increased placental FATP4 protein expression[J]. Reprod Sci,2020,27(10):1909-1919.
[32] Mangwiro YTM, Cuffe JSM, Briffa JF, et al. Maternal exercise in rats upregulates the placental insulin-like growth factor system with diet- and sex-specific responses:Minimal effects in mothers born growth restricted[J]. J Physiol,2018,596(23):5947-5964.
[33] Chen Y, Ma G, Hu Y, et al. Effects of maternal exercise during pregnancy on perinatal growth and childhood obesity outcomes: A Meta-analysis and Meta-regression[J]. Sports Med,2021, 51(11):2329-2347.
[34] Mcmillan AG, May LE, Gaines GG, et al. Effects of aerobic exercise during pregnancy on 1-month infant neuromotor skills[J]. Med Sci Sports Exerc,2019,51(8):1671-1676.
[35] Millard LAC, Lawlor DA, Fraser A, et al. Physical activity during pregnancy and offspring cardiovascular risk factors:Findings from a prospective cohort study[J]. BMJ Open,2013,3(9):e3574.
[36] Meireles ALF, Segabinazi E, Spindler C, et al. Strength training during pregnancy influences hippocampal plasticity but not body development in neonatal rats[J]. J Musculoskelet Neuronal Interact,2021,21(2):279-286.
[37] Jukic AMZ, Lawlor DA, Juhl M, et al. Physical activity during pregnancy and language development in the offspring[J]. Paediatr Perinat Epidemiol,2013,27(3):283-293.
[38] Polańska K, Muszyński P, Sobala W, et al. Maternal lifestyle during pregnancy and child psychomotor development Polish mother and child cohort study[J]. Early Hum Dev,2015,91(5):317-325.

胎儿宫内发育迟缓的危险因素及孕期运动对其干预作用的研究进展

Research progress in the risk factors of fetal intrauterine growth retardation and the intervention effect of exercise during pregnancy

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	刘永莉. 脐血中丙二醛、晚期氧化蛋白产物表达水平与胎儿窘迫及不良结局发生的相关性[J]. 中国儿童保健杂志, 2020, 28(7): 737-739.
[2]	董慧芳, 王银娟, 范旭方, 李文丽, 徐发林. 双胎发育不均衡早产儿早期并发症及纠正年龄12月内神经系统预后分析[J]. 中国儿童保健杂志, 2020, 28(3): 308-311.
[3]	谢华,杨凡. 小于胎龄儿流行病学及病因学研究进展[J]. 中国儿童保健杂志, 2019, 27(3): 285-288.
[4]	张勇, 王朝晖, 李燕晖. 宫内发育迟缓对早产儿体格发育的影响[J]. 中国儿童保健杂志, 2019, 27(12): 1345-1348.
[5]	郑俊虎, 潘益匆, 柯汝淑, 陈洪, 邹跃玲, 胡晓娜, 王大化, 钱定良. 脐血血清促代谢因子水平与胎儿生长发育的关系[J]. 中国儿童保健杂志, 2019, 27(10): 1075-1078.
[6]	刘敬. 胎膜早破对新生儿多器官系统的损害与临床管理[J]. 中国儿童保健杂志, 2017, 25(11): 1081-1085.
[7]	郑军,王晓鹏. 妊娠期高血压对胎儿及新生儿的影响[J]. 中国儿童保健杂志, 2017, 25(11): 1086-1089.
[8]	黄秀娟,宋娟,朱锦渊,杨翠萍,杨悦. 早期运动干预对胎儿生长受限儿的疗效观察[J]. 中国儿童保健杂志, 2016, 24(7): 767-769.
[9]	李荣,陈银花,高修成,赵卫华,田国英,李晓南. 孤立性侧脑室增宽胎儿出生后智力与运动发育的研究[J]. 中国儿童保健杂志, 2016, 24(6): 655-657.
[10]	宗璐,苟文丽,黄谱,薛茜,吕晔. 围孕期复合微营养素补充对仔鼠宫内生长受限的作用及胎盘细胞凋亡的影响[J]. 中国儿童保健杂志, 2016, 24(4): 373-376.
[11]	马宁,李丽华. 胎儿期环境因素对脑发育的影响[J]. 中国儿童保健杂志, 2015, 23(8): 821-823.
[12]	张金,张慧,邢燕,王新利. 宫内发育迟缓大鼠早期追赶生长与胰岛素敏感性变化的关系[J]. 中国儿童保健杂志, 2015, 23(6): 595-598.
[13]	高建,宋慧,段永恒,贾秋利,林圣,刘志强,张玲华,谢立春,曾序春,谷学英,段山. 深圳市202例孤独症儿童出生前后状况调查及影响因素分析[J]. 中国儿童保健杂志, 2015, 23(3): 319-320.
[14]	李廷玉. 胎儿环境暴露与儿童早期发育[J]. 中国儿童保健杂志, 2015, 23(10): 1009-1010.
[15]	宗璐,郭玉琳,苟文丽,帖迎春,吕晔,黄谱. 孕期补锌对胎儿生长受限仔鼠学习记忆能力改变的研究[J]. 中国儿童保健杂志, 2015, 23(10): 1047-1050.