人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究

中国儿童保健杂志 ›› 2011, Vol. 19 ›› Issue (1): 65-67.

人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究

黄于娟,黎海芪

重庆医科大学附属儿童医院儿童保健科,重庆 400014

收稿日期:2010-08-23 发布日期:2011-01-06 出版日期:2011-01-06
通讯作者: 黎海芪,E-mail:haiqili@hotmail.com
作者简介:黄于娟(1982-),女,云南人,医师,医学硕士,主要研究方向为儿童营养

Correlation between contents of polyunsaturated fatty acid in human breast milk and food allergy in infants

HUANG Yu-juan, LI Hai-qi

Department of Child Health Care, Children's Hospital of Chongqing Medical University, Chongqing 400014, China

Received:2010-08-23 Online:2011-01-06 Published:2011-01-06

摘要/Abstract

摘要： 【目的】研究人乳多不饱和脂肪酸(polyunsaturated fatty acid, PUFA)含量与婴儿发生食物过敏的关系。【方法】采集3~6月人乳喂养婴儿母亲的乳汁,高效液相色谱法法检测其中α-LNA、DHA(n-3组)和LA、AA含量(n-6组);按R.Sporik标准确立婴儿食物过敏,比较食物过敏与正常婴儿母亲乳汁中PUFA含量的差异性。【结果】 31例3~6月龄人乳喂养婴儿中10例发生食物过敏,过敏婴儿母亲乳汁中LA、AA及α-LNA含量增高(P<0.05)、DHA含量差异无统计学意义。【结论】食物过敏婴儿的母亲乳汁中α-LNA、LA、AA含量升高,提示人乳PUFA代谢异常可能与婴儿发生食物过敏有关。

关键词: 人乳, 多不饱和脂肪酸, 食物过敏, 婴儿

Abstract: 【Objective】 To explore the correlation between contents of α-LNA、DHA、AA and LA in human milk and the development of food allergy in infants. 【Methods】 Cross-sectional study was conducted; breastfed infants aged 3~6 months were enrolled as well as their mothers; human milk samples were collected in the out-patient clinic, contents of PUFAs in human milk were analysed with HPLC method. Infants were diagnosed as food allergy according to R.Sporik's method in our out-patient clinic. 【Results】 10 infants were diagnosed as food allergy, and 21 normal as control. Contents of α-LNA、AA and LA in human milk of food-allergy group were higher than those in control group(P<0.05), except the contents of DHA. 【Conclusions】 The results suggest that human milk rich in n-6 PUFA such as LA and AA may be a risk factor to the development of food allergy in infants.

Key words: maternal milk, polyunsaturated fatty acid, food allergy, infant

中图分类号:

R174

黄于娟,黎海芪. 人乳多不饱和脂肪酸含量与婴儿食物过敏关系的研究[J]. 中国儿童保健杂志, 2011, 19(1): 65-67.

HUANG Yu-juan, LI Hai-qi. Correlation between contents of polyunsaturated fatty acid in human breast milk and food allergy in infants[J]. journal1, 2011, 19(1): 65-67.

参考文献

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