Rho-ROCK信号通路研究进展

中国儿童保健杂志 ›› 2012, Vol. 20 ›› Issue (9): 822-825.

Rho-ROCK信号通路研究进展

刘颖综述, 刘敬审校

北京军区总医院附属八一儿童医院新生儿重症监护中心,北京 100700

收稿日期:2012-03-23 发布日期:2012-09-06 出版日期:2012-09-06
通讯作者: 刘敬,E-mail:Liujingbj@sina.com
作者简介:刘颖(1987-),女,安徽人,住院医师,硕士研究生,主要研究方向为新生儿疾病
基金资助:
国家自然科学基金资助项目(81170577)

Received:2012-03-23 Online:2012-09-06 Published:2012-09-06

摘要/Abstract

摘要： Ras同源基因-Rho相关螺旋卷曲蛋白激酶(Ras homolog gene/a Rho-associated coiled coil-forming protein kinase,Rho-ROCK)信号途径是中枢神经系统中普遍存在的一条通路,是介导抑制性信号阻断中枢神经细胞再生的重要途径。中枢神经损伤后再生困难的重要原因是其周围环境中存在强烈抑制再生的物质,并通过该途径介导神经再生障碍。熟悉Rho-ROCK信号通路及这些抑制性介质的作用,对研究神经损伤后再生与修复等具有重要意义。

中图分类号:

R722

刘颖综述, 刘敬审校. Rho-ROCK信号通路研究进展[J]. 中国儿童保健杂志, 2012, 20(9): 822-825.

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