胰岛素样生长因子-I与甲状腺功能减低症的关系

摘要/Abstract

摘要： 胰岛素样生长因子-I (insulin-like growth factor-I,IGF-I)和甲状腺激素都具有促进物质代谢、促进生长发育的作用,两者相互作用,相互调节。IGF-I与自身免疫性甲状腺疾病的发生、发展有密切关系。IGF-I水平可能与甲状腺癌的恶性度有关。甲状腺功能减低症患儿治疗前血清甲状腺激素和IGF-I 水平较低,有效治疗后甲状腺激素和IGF-I均升高,IGF-I可作为甲状腺功能减低症患儿疗效判断的一项观察指标。

中图分类号:

R722

郑敏综述, 蔡稔审校. 胰岛素样生长因子-I与甲状腺功能减低症的关系[J]. 中国儿童保健杂志, 2013, 21(2): 158-160.

参考文献

[1] Zivar S,Farhad M,Mohammad N,et al.Insulin-like growth factor-1 and insulin-like growth factor binding proteins in cerebrospinal fluid during the development of mouse embryos[J].Journal of Clinical Neuroscience,2009,16(7):950-953.
[2] Santen RJ,Fan P,Yue W,et al.Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and resistant breast cancer cells[J].Steroids,2009,74(7):586-594.
[3] Wathes DC,Cheng Z,Fenwick MA,et al.Influence of energy balance on the somatotrophic axis and matrix metalloproteinase expression in the endometrium of the postpartum dairy cow[J].Reproduction,2011,141(2):269-281.
[4] Koketsu R,Suzukawa M,Kawakami A,et al.Activation of basophils by stem cell factor:comparison with insulin-like growth factor-I[J].J Investig Allergol Clin Immunol,2008:18(4):293-299.
[5] Wang D,Liu YL,Lü XD,et al.Expression of ghrelin and insulin-like growth factor-1 in immature piglet model of chronic cyanotic congenital heart defects with decreased pulmonary blood flow[J].Chin Med J (Engl),2011,124(15):2354-2360.
[6] Nanez A,Ramos IN,Ramos KS.A mutant ahr allele protects the embryonic kidney from hydrocarbon-induced deficits in fetal programming[J].Environ Health Perspect,2011,119(12):1745-1753.
[7] Kamei H,Ding Y,Kajimura S,et al.Role of IGF signaling in catch-up growth and accelerated temporal development in zebrafish embryos in response to oxygen availability[J].Development,2011,138(4):777-786.
[8] Narimatsu N,Harada N,Kurihara H,et al.Donepezil improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus[J].J Pharmacol Exp Ther,2009,330(1):2-12.
[9] Bishop NA,Lu T,Yankner BA.Neural mechanisms of ageing and cognitive decline[J].Nature,2010,464(7288):529-535.
[10] Quinlan P,Nordlund A,Lind K,et al.Thyroid hormones are associated with poorer cognition in mild cognitive impairment[J].Dement Geriatr Cogn Disord,2010,30(3):205-211.
[11] Al-Delaimy WK,von Muhlen D,Barrett-Connor E.Insulinlike growth factor-1,insulinlike growth factor binding protein-1,and cognitive function in older men and women[J].J Am Geriatr Soc,2009,57(8):1441-1446.
[12] Wang L,Shao YY,Ballock RT.Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of beta-catenin signaling[J].J Bone Miner Res,2010,25(5):1138-1146.
[13] R_nning B,Mortensen AS,Moe B,et al.Food restriction in young Japanese quails:effects on growth,metabolism,plasma thyroid hormones and mRNA species in the thyroid hormone signalling pathway[J].J Exp Biol,2009,212(19):3060-3067.
[14] Boas M,Hegedüs L,Feldt-Rasmussen U,et al.Association of thyroid gland volume,serum insulin-like growth factor-I,and anthropometric variables in euthyroid prepubertal children[J].J Clin Endocrinol Metab,2009,94(10):4031-4035.
[15] Tsui S,Naik V,Hoa N,et al.Evidence for an association between thyroid-stimulating hormone and insulin-like growth factor 1 receptors:a tale of two antigens implicated in Graves' disease[J].J Immunol,2008,181(6):4397-4405.
[16] Zhao SX,Tsui S,Cheung A,et al.Orbital fibrosis in a mouse model of Graves' disease induced by genetic immunization of thyrotropin receptor cDNA[J].J Endocrinol,2011,210(3):369-377.
[17] Scacchi M,Andrioli M,Carzaniga C,et al.Elastosonographic evaluation of thyroid nodules in acromegaly[J].Eur J Endocrinol,2009,161(4):607-613.
[18] Eskes SA,Endert E,Fliers E,et al.Prevalence of growth hormone deficiency in Hashimoto's thyroiditis[J].J Clin Endocrinol Metab,2010,95(5):2266-2270.
[19] Kirovski D,Lazarevic M,Baricevic-Jones I,et al.Effects of peroral insulin and glucose on circulating insulin-like growth factor-1,its binding proteins and thyroid hormones in neonatal calves[J].Can J Vet Res,2008,72(3):253-258.
[20] Boas M,Frederiksen H,Feldt-Rasmussen U,et al.Childhood exposure to phthalates:associations with thyroid function,insulin-like growth factor I,and growth[J].Environ Health Perspect,2010,118(10):1458-1464.
[21] Gejao MG,Ferreira AT,Silva GK,et al.Communicative and psycholinguistic abilities in children with phenylketonuria and congenital hypothyroidism[J].J Appl Oral Sci,2009,17(S):69-75.
[22] Rovet JF.Children with congenital hypothyroidism and their siblings:do they really differ[J].Pediatrics,2005,115(1):52-57.
[23] Gejao MG,Lamqnica DA.Development skills in children with congenital hypothyroidism:focus on communication[J].Pro Fono,2008,20(1):25-30.
[24] Orbeck B,Sundet K,Jorgensen JV,et al.Congenital hypothyroidism and the impact of thyroxine treatment[J].Tidsskr Nor Laegeforen,2005,125(22):3101-3103.