关键词: 原发性高血压, 超声心动图, 左心室结构, 左心室功能, 儿童

Abstract: Objective To study the features of left ventricular structure and function in children and adolescent with essential hypertension (EH). Method Cardiac structural parameters and function were measured in 37 EH children with echocardiography (EH group) and 42 healthy children were studied as controls. Results Compared with control group, left ventricular end-diastolic diameter(LVEDD), left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic posterior wall thickness (LVPWT), interventricular septum end-diastolic thickness (IVST), left ventricular mass (LVM) and left ventricular mass index (LVMI) were all significantly higher than those in control group (P<0.05).While ejection fraction (EF) and left ventricular fractional shortening (FS) were significantly lower in EH group compared with control group (P<0.05).Descending E peak in end diastole was lower in the EH group, but with no statistical significance (P>0.05).In EH group, peak in end diastole was enhanced (P<0.05), and E/A ratio was significantly lower(P<0.05).Some of the patients were found to develop left ventricular hypertrophy. Conclusion In children with EH, the heart as a target organ had developed some degree of structural and functional changes.

Key words: essential hypertension, echocardiography, left ventricular structure, left ventricular function, children