关键词: 肥胖, 代谢综合征, 胰岛素抵抗, 儿童

Abstract: Objective To investigate the prevalence of metabolic syndrome in obese children and adolescents and the clinical characteristic in outpatient. Method According to the newest diagnosis criteria of metabolic syndrome in children in China, the databases of the clinical and experimental characteristics in simple obesity children and adolescents diagnosed from 2008 to 2010 in the First Affiliated Hospital of SUN Yat-sen University were analysed. Results Eighty-eight patients with simple obesity were enrolled in the study, 63 were above 10 years old 60 had at least one component of metabolic syndrome, 8 (12.7%) were diagnosed as metabolic syndrome, 28 (44.44%) had one component, 24 (38.09%) had 2 components.Among 88 obese children, 25 were aged 6 to 10 year-old, of which, 11 (44%) had cardiovascular risk factors. Conclusions Obese children in outpatient has high prevalence of the metabolic syndrome.There are high prevalences of insulin resistance, hyperinsulinemia and impaired fasting glucose in patients with the metabolic syndrome.

Key words: obesity, metabolic syndrome, insulin resistance, child