关键词: 极低出生体重儿, 贫血, 医源性失血, 输血

Abstract: Objective To explore the anemia onset time and influencing factors in very low birth weight infants(VLBWI).Methods A total of 147 VLBWI hospitalized in neonatal ward of affiliated hospital of Qingdao University from January 2012 to December 2013 were divided into 4 groups according to the anemia time.The perinatal factors with the anemia were analysed respectively in the groups. Results The average time for onset of anemia was (12.26±7.95)d.The incidences of early anemia was 29.9%,the late anemia was 70.1%.Compared with each other of the four VLBWI groups,accumulation of blood loss and the amount of blood transfusion within 4 weeks after birth in VLBWI had statistically significant differences(P＜0.01).Compared with each other groups,the level of initial hemoglobin and the initial HCT of VLBWI had statistically significant differences(P＜0.01).The differences in the following aspects:placental abruption,fetal distress,intracranial hemonhage of the newborn (ICH),complications during neoynatal stage were statistically significant (P＜0.05).Logistic analysis showed that the latrogenic blood loss and the level of Hb related with anemia.Conclusion s Anemia is a common complication in the VLBWI.The latrogenic blood loss and the level of Hb are important high risk factors of the occurrence of anemia.Blood transfusion is the routine even the preferred method to cure anemia in VLBWI.

Key words: very low birth weight, anemia, latrogenic blood loss, transfusion