关键词: 孤独症谱系障碍, 发育性语言延迟, 发病相关因素, 回顾性研究

Abstract: 【Objective】 To study the differences between autism spectrum disorders(ASD) and developmental language disorders(DLD) in pathogenesis related factors(risk factors and clinical manifestations). 【Methods】 This retrospective study compared risk factors and clinical manifestations of 39 toddlers(aged 2-5y) with ASD and 46 toddlers with DLD using detailed questionnaires containing 16 items, then analysed data by t test, chi-square test, rank test . 【Results】 Children with ASD had prominent impairments in socialization language, especially, in the age calling mother(or other caregivers) consciously(P<0.05). While there were no differences in other factors(including: premature birth, birthrank, birth mode, asphyxia, birth weight, birth injury, head injury, convulsion, major illnesses, caregivers,parents reproductive age, family history)(P>0.05). Children with ASD were often observed and sent to doctors because of language delay(78.28%), social problems(78.28%), behavioral problems(36.57%) . And the mean age of first diagnosis was 39 months. 【Conclusions】 Children with ASD have prominent impairments in socialization language, more sever than children with DLD. The language delay and social problems are more likely to be observed by caregivers of children with ASD. The first diagnosis of children with ASD is often delayed .

Key words: autistic spectrum disorders, developmental language disorder, risk factors, retrospective study