关键词: 孤独症谱系障碍, PEP-3, 反应模式

Abstract: Objective To explore the developmental profile of children with autism spectrum disorder (ASD) on PEP-3. Methods A total of 52 children with ASD who were divided into two groups according their intelligence level, low-function autism (LFA) and high-functioning autism (HFA), and 26 aged-matched typically children were evaluated by PEP-3 (each group included 23 boys and 3 girls, aged 2~5 years old). Results LFA children exhibited a greater developmental delay in all subtests on PEP-3 as compared with typically children (P<0.001).The scores and developmental ages on the cognitive verbal/preverbal (CVP) and gross motor (GM) subtests were lower in HFA group than TD group (P<0.05).LFA group significantly scored lower than HFA group on CVP, expressive language (EL), receptive language (RL), fine motor (FM) and visual motor imitation (VMI) subtests (P<0.05).For the communication composite and motor composite, children with LFA exhibited "low-high" trend (51.68±14.34 VSs 75.08±9.00, P<0.001), while HFA group presented "balanced" phenomenon (91.40±12.93 VS 87.02±11.66, P=0.205). Conclusion Children with ASD of different intelligence level exhibites differently on PEP-3.

Key words: aautism spectrum disorders, PEP-3, developmental profile