关键词: 18月龄, 幼儿, 维生素D, 神经发育

Abstract: Objective To explore the effect of serum vitamin D levels on the neural development in 18 months old infants,and to provide theory basis for prevention and intervention. Methods Serum vitamin D levels of 1 283 infants aged 18 months were detected and divided into three groups (deficiency,insufficiency,and normal group)from June 2014 to May 2017.They were assessed with Developmental Screen Test (DST),an intellectual developmental screening test developed by Pediatric Hospital of Fudan University in Shanghai,and the differences of developmental quotient,exercise capacity,social adaptation,intelligence of three groups were compared. Results 1)The detection rates of vitamin D deficiency,insufficiency,and normal range were 3.35%,30.16% and 66.48% respectively.The difference on serum vitamin D was not significant in three groups (t=3.507,P>0.05).2)The values of the intelligence in the deficiency group were significantly lower than those of normal group (t=5.657,P<0.05). Conclusion Vitamin D dificiency has a negative effect on neuropsychological development,and Vitamin D should be promptly added to infants of vitamin D deficiency.

Key words: 18 months old, infants, vitamin D, neural development