关键词: 儿童哮喘, 患者报告结局, 概念模型, 量表结构

Abstract: Objectives To develop a conceptual model for childhood asthma patient reported outcomes reported by parents, and to explore the structure of patient reported outcomes scale preliminarily, in order to provide basis for the compilation and evaluation of the scale.Methods A conceptual model, initial dimensions and items pool were developed by literature review combined with expert consultation and target group interview methods. The items were preliminarily screened and revised according to the test results of 30 parents of asthmatic children and the evaluation opinions of 5 experts, and then an initial questionnaire containing 72 items was formed. Totally 212 parents of asthmatic children were investigated, and the items of initial questionnaire were screened by using the classical test theory methods, combined with parallel analysis, exploratory factor analysis methods and expert advice, finally the structure of childhood asthma patient reported outcomes scale reported by parents was identified.Results A four primary indicators and eight secondary indicators conceptual model was constructed. Based on that, an initial questionnaire containing 72 items was compiled and a field investigation was carried out. The items screening, parallel analysis and exploratory factor analysis showed that five common factors were extracted, and the cumulative variance contribution rate was 51.6%. The five common factors reflected children′s physical condition, psychological status, daily activities, behavior restrictions and family influence.Conclusions The extracted five common factors were covered in the conceptual model and could explain the impact of asthma on children. The scale of childhood asthma patient reports outcomes reported by parents should be compiled in 5 dimensions, including physical condition, psychological state, daily activities, behavior restrictions and family influence.

Key words: childhood asthma, patient reported outcomes, conceptual model, scale structure