正常328名1~6月龄婴儿脑干听觉诱发电位结果分析

doi:10.11852/zgetbjzz2018-0897

中国儿童保健杂志 ›› 2019, Vol. 27 ›› Issue (3): 311-313.DOI: 10.11852/zgetbjzz2018-0897

正常328名1~6月龄婴儿脑干听觉诱发电位结果分析

张萍,王小燕,汪鸿,赵职卫

湖北省妇幼保健院儿童保健科,湖北武汉 430070

收稿日期:2018-07-01 修回日期:2018-10-11 发布日期:2019-03-20 出版日期:2019-03-20
通讯作者: 王小燕,E-mail:wxyask@163.com
作者简介:张萍(1985-),女,湖北人,主治医师,硕士研究生,主要研究方向儿童发育行为问题。
基金资助:
中国疾病预防控制中心妇幼保健中心儿童早期发展适宜技术研究基金(2017FYE004)

Analysis of the results of auditory brainstem response in 328 normal infants aged 1-6 months

ZHANG Ping,WANG Xiao-yan,WANG Hong,ZHAO Zhi-wei

Maternal and Child Health Hospital of Hubei Province,Wuhan,Hubei 430070,China

Received:2018-07-01 Revised:2018-10-11 Online:2019-03-20 Published:2019-03-20
Contact: WANG Xiao-yan,E-mail:wxyask@163.com

摘要/Abstract

摘要： 目的探讨1~6月龄正常婴儿脑干听觉诱发电位(ABR)的变化规律,建立婴幼儿ABR波Ⅰ、Ⅲ、Ⅴ潜伏期及Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ-Ⅴ波间期的正常值范围,为临床工作提供依据。方法 2017年1月-2018年1月对328名听力正常婴儿和40例成人进行ABR测试。结果 1~6月龄婴儿Ⅰ波潜伏期分别为(1.65±0.07)、(1.59±0.07)、(1.59±0.05)、(1.57±0.07)、(1.56±0.05)ms和(1.54±0.06)ms,该指标至5月龄时已与成人值(1.53±0.02)ms相近(P>0.05);Ⅲ、Ⅴ波潜伏期及Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ-Ⅴ波间期随月龄增长而缩短,至6月龄时各值分别为(4.04±0.12)、(6.11±0.13)、(2.50±0.11)、(2.07±0.13)、(4.57±0.12)ms,但仍未达到成人水平(3.90±0.08)、(5.77±0.07)、(2.37±0.08)、(1.87±0.11)ms和(4.24±0.07)ms,差异有统计学意义(P<0.05)。各波潜伏期及波间期无性别及左右耳差异(P>0.05)。结论建立1~6月龄婴儿ABR潜伏期及波间期正常值标准,为听力及发育障碍的早期诊断和随访检测提供可靠依据。

关键词: 脑干听觉诱发电位, 正常值范围, 1~6月龄婴儿

Abstract: Objective To investigate the characteristics of auditory brainstem response(ABR) in normal infants aged 1~6 months,and to establish a normal range of the peak latencies(PLs) of wave Ⅰ、Ⅲ、Ⅴ and interpeak latencies(IPLs) of Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ-Ⅴ, in order to provide basis for clinic work. Methods Totally 328 infants with normal hearing and 40 adults were tested by ABR from January 2017 to January 2018. The PLs of wave Ⅰ、Ⅲ、Ⅴ and IPLs of Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ-Ⅴ from infants of different age groups and ears on different sides were compared. Results The PL of wave I in infants aged 1-6 months was(1.65±0.07),(1.59±0.07),(1.59±0.05),(1.57±0.07),(1.56±0.05) ms and(1.54±0.06) ms,respectively. And the value at the age of 5 months was close to that of adults [(1.53±0.02)ms,P>0.05)]. The PLs of wave Ⅲ、Ⅴ and the IPLs of Ⅰ-Ⅲ、Ⅲ-Ⅴ、Ⅰ-Ⅴ became shorter with the increase of age,which were(4.04±0.12),(6.11±0.13),(2.50±0.11),(2.07±0.13)ms and(4.57±0.12)ms respectively in infants of 6 months old. But these values were still significantly longer than those of adults[(3.90±0.08),(5.77±0.07),(2.37±0.08) ms,(1.87±0.11)ms and(4.24±0.07)ms,P<0.05)]. No significant differences were found between ages or different side of ears(P>0.05). Conclusion The establishment of normalrange of ABR wave for the infants aged 1 to 6 months will provide reliable basis for early diagnosis and follow-up detection of hearing and development disorders.

Key words: auditory brainstem response, normal range, infants aged 1-6 months

中图分类号:

R722

张萍,王小燕,汪鸿,赵职卫. 正常328名1~6月龄婴儿脑干听觉诱发电位结果分析[J]. 中国儿童保健杂志, 2019, 27(3): 311-313.

ZHANG Ping,WANG Xiao-yan,WANG Hong,ZHAO Zhi-wei. Analysis of the results of auditory brainstem response in 328 normal infants aged 1-6 months[J]. journal1, 2019, 27(3): 311-313.

参考文献

[1] 王小燕,汪鸿,赵职卫.脑干听觉诱发电位在高危儿脑损伤的动态监测[J].中国儿童保健杂志,2018,26(7):755-757.
[2] 冀飞.听觉诱发电位临床应用进展[J].中华耳科学杂志,2017,15(2):138-146.
[3] 李兴启,王秋菊.听觉诱发反应及应用[M].2版.北京:人民军医出版社,2015:179-189.
[4] Amin SB,Vogle-Elias D,Orlando M,et al.Auditory neural myelination is associated with early childhood language development in premature infants[J].Early Hum Dev,2014,90(10):673-678.
[5] Judith MG,Bernard ZK,Robert LF.Neonatal brainstem function and 4-month arousal-modulated:attention are jointly associated with autism[J].Autism Res,2013,6:11-22.
[6] 葛海静,章依文,刘秀梅,等.语言发育迟缓儿童中的听力问题探讨[J].中国妇幼保健,2013,21(1):79-82.
[7] Miron O.Prolonged auditory brainstem responses in infants with autism[J].Autism Res,2016,9(6):689-695.
[8] 樊洁敏,余红,赵军.不同月龄婴儿ABR正常值分析[J].听力学及言语疾病杂志,2015,23(5):471-472.
[9] 茅学英,陶峥,顾宇,等.不同年龄正常听力新生儿和婴幼儿听性脑干反应波潜伏期分析[J].听力学及言语疾病杂志,2014,22(3):239-241.
[10] 郑周数,陈淑飞,邵小飞,等. 1~6月龄正常婴幼儿听性脑干反应检测结果分析[J].听力学及言语疾病杂志,2013,21(6):593-595.
[11] 余崇仙,杨克林,张晓敏,等.3~4月龄及5~6月龄婴儿听性脑干反应的正常值分析[J].山东大学耳鼻喉眼学报,2010,24(4):17-20.
[12] Bahram J,Mohd H,Mohd N.Gender differences in binaural speech-evoked auditory brainstem response:are they clinically significant? [J/OL].Braz J Otorhinolar,in press.https://doi.org/10.1016/j.bjorl.2018.04.005
[13] Stuart A,Yang EY.Gender effects in auditory brainstem response to air and bone-conducted cricks in neonates[J].J Commun Disord,2001,34(3):229-239.

正常328名1~6月龄婴儿脑干听觉诱发电位结果分析

Analysis of the results of auditory brainstem response in 328 normal infants aged 1-6 months

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