关键词: VD缺乏, 相关因素, 神木地区, 儿童

Abstract: Objective To understand the serum level of 25-hydroxy vitamin D [25-(OH)D] in children from Shenmu,to evaluate the risk degree and to find out the influencing factors,thereby providing theoretical basis for the prevention and treatment of vitamin D deficiency in this area. Methods A total of 687 children were selected for health examination in child health clinic from January 2016 to December 2017.Serum 25-(OH)D₃ concentrations of children was tested by chemiluminescence immunoassay,and the influencing factors were analyzed. Results The maximum value of 25-(OH)D in 687 children was 96.9 ng/ml,and the minimum value was 2 ng/ml,with the average level of (32.59±13.14) ng/ml.The number of children with vitamin D deficiency,insufficiency,appropriate level of vitamin D was 120(17.5%),169(24.6%) and 398(57.9%),respectively.No children existed excessive vitamin D level or vitamin D intoxication.Single factor analysis indicated that vitamin D level was related to age,season,daily time for outdoor activity,previous supplementation of vitamin D,duration of vitamin D supplementation,vitamin D supplementation over the past three months(P＜0.05).Logistic regression analysis showed that daily outdoor activity time for 30 min to 2 hours (OR=0.43,95%CI:0.22-0.84,P=0.03) and vitamin D supplementation for 3 months to one year (OR=0.12,95%CI:0.05-0.28,P<0.001) were protective factors for vitamin D deficiency. Conclusion The protective factor of vitamin D deficiency is the duration of outdoor activities and vitamin D supplementation.The key to reduce vitamin D deficiency is prevention,and health education is supposed to be strengthened.

Key words: vitaminDdeficiency, Shenmu, children