关键词: 维生素A缺乏, 临床维生素A缺乏, 儿童

Abstract: Objective To investigate the serum level of vitamin A in children aged 0 to 14 years in Fushun city,so as to provide reasonable scientific basis for vitamin A supplementation and reference for clinical diagnosis and treatment. Methods Totally 6 766 healthy children aged 0 to 14 years,who took physical examination in Fushun Mining Bureau General Hospital,were recruited in this study from January,2015 to December,2018.Serum vitamin A level was tested by high performance liquid chromatography. Results The detection rates of subclinical vitamin A deficiency and suspicious subclinical vitamin A deficiency were 17.85% (1 208/6 766) and 43.26%(2 927/6 766).There was significantly difference on serum vitamin A level from 2015 to 2018(P＜0.05).The detection rates of suspicious subclinical vitamin A deficiency and subclinical vitamin A deficiency were 45.3% and 10.5%,respectively,significantly lower than before.There was no significant difference on serum vitamin A level between boys and girls (P＞0.05).But significant difference existed among different seasons(P＜0.05),and vitamin A level was highest in autumn.There was also significant difference on serum level of vitamin A among different age groups (P<0.05).Serum vitamin A deficiency rate gradually decreased with the increasing of age.Serum level of vitamin A in children under 1 month old and aged 1 to 6 months was significantly lower than that in other age groups.However,vitamin A level of children aged 6 to 14 years was in the normal range. Conclusions Serum vitamin A level of children aged 0 to 14 years in Fushun is still lower,especially in infants aged 0 to 6 months.Thus,more attention should be paid to the dietary structure adjustment and rational vitamin A supplementation in order to prevent vitamin A deficiency.

Key words: vitamin A deficiency, subclinical vitamin A defieiency, children