关键词: 脑瘫, 儿童, 营养状况, 免疫, 个体化干预

Abstract: Objective To evaluate the nutritional status of children with cerebral palsy by anthropometry,and to test the levels of humoral immune factors and analyze the correlation with nutritional status,so as to provide reference for clinical implementation of individualized nutrition services. Methods Children with cerebral palsy aged 1 to 5 years and hospitalized in the Department of Child Rehabilitation of the Third Affiliated Hospital of Zhengzhou University were selected as the study objects. The nutritional status of the children was evaluated by Z-score method,and the levels of humoral immune factors were measured. All children were given nutritional treatment intervention,and the improvement of nutritional indicators was detected after intervention. Results A total of 90 children with cerebral palsy were included for nutritional assessment and were given individualized nutrition intervention. The incidence of malnutrition was 53.3%(48/90),including 33.3% of low weight,54.2% of growth retardation,20.8% of weight loss and 16.7% of overweight or obesity. There were significant differences in weight,WAZ,IgG and IgM levels among children with mild,moderate and severe cerebral palsy (F=3.321,3.964,16.955,5.596, P<0.05). After intervention,the weight and WAZ were higher than those before intervention,and the difference was significant (t=2.236,2.280,P<0.05). Conclusions There is a high prevalence rate of malnutrition and nutritional diseases in children with cerebral palsy. The more serious the disease is,the worse the nutritional status is,and the lower the levels of humoral immune factors IgG and IgM will be. And individualized nutritional intervention plays a positive role in improving recent nutritional status of children with cerebral palsy.

Key words: cerebral palsy, children, nutritional status, immune, individualized intervention